256504-50-4Relevant academic research and scientific papers
Probes for narcotic receptor mediated phenomena. 26. Synthesis and biological evaluation of diarylmethylpiperazines and diarylmethylpiperidines as novel, nonpeptidic δ opioid receptor ligands
Zhang, Xiaoyan,Rice, Kenner C.,Calderon, Silvia N.,Kayakiri, Hiroshi,Smith, Larren,Coop, Andrew,Jacobson, Arthur E.,Rothman, Richard B.,Davis, Peg,Dersch, Christina M.,Porreca, Frank
, p. 5455 - 5463 (1999)
We recently reported (+)-4-[(αR)-α-{(2S,5R)-4-allyl-2,5- dimethyl-1-piperazinyl}-3-methoxybenzyl]-N,N-diethylbenzamide (1b, SNC80) as a novel nonpeptidic δ receptor agonist and explored the structure-activity relationships (SAR) of a series of related der
