58287-77-7

Basic information

• Product Name: Benzamide, N,N-diethyl-4-formyl-
• CAS NO: 58287-77-7
• Molecular Formula: C12H15NO2
• Molecular Weight: 205.257
• Mol File: 58287-77-7.mol
• Article Data: 19

Chemical Properties

• CAS DataBase Reference: Benzamide, N,N-diethyl-4-formyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzamide, N,N-diethyl-4-formyl-(58287-77-7)
• EPA Substance Registry System: Benzamide, N,N-diethyl-4-formyl-(58287-77-7)

Safety Data

• Hazardous Substances Data: 58287-77-7(Hazardous Substances Data)

Upstream product

• 1244044-89-0 N'-cyclohexyl-N,N-diethylterephthalamide 
• 619-66-9 4-Carboxybenzaldehyde 
• 109-89-7 diethylamine 
• 543-27-1 isobutyl chloroformate 
• 79-37-8 oxalyl dichloride 
• 3282-30-2 pivaloyl chloride 
• 121-44-8 triethylamine 
• 16173-52-7 4-formylbenzoyl chloride 

Downstream Products

• 857252-37-0 N,N-diethyl-4-(5,6,7-trimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl)benzamide 
• 857252-34-7 N,N-diethyl-4-(5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinolin-5-yl)benzamide 
• 857252-28-9 4-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl)-N,N-diethylbenzamide 
• 356066-39-2 1-(4-Diethylcarbamoylphenyl)-1-(2-methoxyphenyl)methyl alcohol 
• 155765-75-6 4-[(3-{[tert-butyl(dimethyl)silyl]oxy}phenyl)(hydroxy)methyl]-N,N-diethylbenzamide 

Relevant articles and documents

Synthesis of Vicinal Quaternary All-Carbon Centers via Acid-catalyzed Cycloisomerization of Neopentylic Epoxides

We report our studies on the development of a catalytic cycloisomerization of 2,2-disubstituted neopentylic epoxides to produce highly substituted tetralins and chromanes. Termination of the sequence occurs via Friedel-Crafts-type alkylation of the remote (hetero)arene linker. The transformation is efficiently promoted by sulfuric acid and proceeds best in 1,1,1,3,3,3-hexafluoroisopropanol (HFIP) as the solvent. Variation of the substitution pattern provided detailed insights into the migration tendencies and revealed a competing disproportionation pathway of dihydronaphthalenes.

DELTA OPIOID AGONIST, MU OPIOID ANTAGONIST COMPOSITIONS AND METHODS FOR TREATING PARKINSON'S DISEASE

The present invention provides for compositions and methods for the treatment of Parkinson's disease comprising a compound of formula (i): or a pharmaceutically effective salt or ester thereof alone or in combination with L-DOPA to provide a synergistic e

Controlled and chemoselective reduction of secondary amides

This communication describes a metal-free methodology involving an efficient and controlled reduction of secondary amides to imines, aldehydes, and amines in good to excellent yields under ambient pressure and temperature. The process includes a chemoselective activation of a secondary amide with triflic anhydride in the presence of 2-fluoropyridine. The electrophilic activated amide can then be reduced to the corresponding iminium using triethylsilane, a cheap, rather inert, and commercially available reagent. Imines can be isolated after a basic workup or readily transformed to the aldehydes following an acidic workup. The amine moiety can be accessed via a sequential reductive amination by the addition of silane and Hantzsch ester hydride in a one-pot reaction. Moreover, this reduction tolerates various functional groups that are usually reactive under reductive conditions and is very selective to secondary amides.