256510-35-7Relevant academic research and scientific papers
The first example of a (1R,2S,5R)-(-)-menthyl chiral auxiliary in intramolecular nitrilimine cycloadditions: Synthesis of enantiopure pyrazolo[1,5-a][4,1]benzoxazepines and pyrazolo[1,5-a][4,1]benzodiazepines
Molteni, Giorgio,Pilati, Tullio
, p. 3873 - 3876 (2007/10/03)
By using (1R,2S,5R)-(-)-menthyl as a chiral auxiliary, we have developed a synthesis of hydrazonoyl chlorides 2 and 8, treatment of which with silver carbonate promoted the in situ generation of the corresponding nitrilimines 3 and 9. The latter underwent
