256638-30-9

Upstream product

• 992-36-9 dibenzyl 3,3'-bis(2-methoxycarbonylethyl)-4,4'-dimethyl-2,2'-pyrromethane-5,5'-dicarboxylate 
• 809-27-8 4,4'-bis-(2-methoxycarbonyl-ethyl)-3,3'-dimethyl-5,5'-methanediyl-bis-pyrrole-2-carboxylic acid 
• 164172-16-1 1,9-diiodo-3,7-bis[2-(methoxycarbonyl)ethyl]-2,8-dimethyldipyrrin 
• 130468-97-2 3-{5-Iodo-2-[5-iodo-3-(2-methoxycarbonyl-ethyl)-4-methyl-1H-pyrrol-2-ylmethyl]-4-methyl-1H-pyrrol-3-yl}-propionic acid methyl ester 
• 20303-31-5 benzyl 4-(2-methoxycarbonylethyl)-3,5-dimethylpyrrole-2-carboxylate 
• 256638-29-6 3-{5-[3-(1-benzyloxy-ethyl)-4-methyl-5-oxo-dihydro-furan-2-ylidenemethyl]-2-[3-(2-methoxycarbonyl-ethyl)-4-methyl-5-(3-methyl-5-oxo-4-vinyl-5H-furan-2-ylidenemethyl)-pyrrol-2-ylidenemethyl]-4-methyl-1H-pyrrol-3-yl}-propionic acid methyl ester 
• 256638-23-0 3-{5-[(Z)-4-Carbamoyl-6-(4-chloro-phenylselanyl)-3-methyl-hex-3-en-1-ynyl]-2-[1-[5-iodo-3-(2-methoxycarbonyl-ethyl)-4-methyl-1H-pyrrol-2-yl]-meth-(Z)-ylidene]-4-methyl-2H-pyrrol-3-yl}-propionic acid methyl ester 
• 256638-25-2 3-{5-((Z)-4-Carbamoyl-3-methyl-hexa-3,5-dien-1-ynyl)-2-[1-[5-iodo-3-(2-methoxycarbonyl-ethyl)-4-methyl-1H-pyrrol-2-yl]-meth-(Z)-ylidene]-4-methyl-2H-pyrrol-3-yl}-propionic acid methyl ester 
• 256638-28-5 3-[2-[5-iodo-3-(2-methoxycarbonyl-ethyl)-4-methyl-1H-pyrrol-2-ylmethylene]-4-methyl-5-(3-methyl-5-oxo-4-vinyl-5H-furan-2-ylidenemethyl)-2H-pyrrol-3-yl]-propionic acid methyl ester 
• 182227-63-0 Z-2-[2-(4-chlorophenylselanyl)ethyl]-3-methylpent-2-en-4-ynoic acid amide 
• 182227-65-2 Z-3-methyl2-vinylpent-2-en-4-ynoic acid amide 

Relevant academic research and scientific papers

New Strategies for the Synthesis of Biologically Important Tetrapyrroles. The "B,C + D + A" Approach to Linear Tetrapyrroles

Linear tetrapyrroles related to phytochrome (1) were prepared in enantiospecific fashion by a new strategy beginning with ring-B,C synthons of type 19 (bis-iododipyrrins). Rings A and D were elaborated by Pd(0)-mediated coupling of 19a with the appropriate alkyne acid or amide derivatives 9 and 20, followed by intramolecular cyclization (method C: BC + D + A → ABCD).