20303-31-5

Usage

Uses

1. Chemical Synthesis Studies:
METHYL 5-(BENZYLOXYCARBONYL)-2,4-DIMETHYL-3-PYRROLEPROPIONATE is used as a key intermediate in the synthesis of various organic compounds. Its unique structure allows for further functionalization and modification, making it a valuable building block for the development of new molecules with potential applications in pharmaceuticals, materials science, and other areas.
2. Pharmaceutical Industry:
In the pharmaceutical industry, METHYL 5-(BENZYLOXYCARBONYL)-2,4-DIMETHYL-3-PYRROLEPROPIONATE is used as a starting material for the synthesis of novel drug candidates. Its versatile chemical structure enables the development of new therapeutic agents with improved efficacy and selectivity, targeting a wide range of diseases and conditions.
3. Materials Science:
METHYL 5-(BENZYLOXYCARBONYL)-2,4-DIMETHYL-3-PYRROLEPROPIONATE can also be utilized in the field of materials science for the development of advanced materials with unique properties. Its incorporation into polymers and other materials can lead to the creation of new materials with enhanced performance characteristics, such as improved mechanical strength, thermal stability, or chemical resistance.
4. Research and Development:
In academic and industrial research settings, METHYL 5-(BENZYLOXYCARBONYL)-2,4-DIMETHYL-3-PYRROLEPROPIONATE serves as a valuable compound for exploring new reaction pathways and understanding the fundamental principles of organic chemistry. Its use in research can lead to the discovery of new synthetic methods, catalysts, and reaction mechanisms, ultimately contributing to the advancement of chemical science.

InChI:InChI=1/C18H21NO4/c1-12-15(9-10-16(20)22-3)13(2)19-17(12)18(21)23-11-14-7-5-4-6-8-14/h4-8,19H,9-11H2,1-3H3

Upstream product

• 99602-66-1 benzyl 3-(2-benzyloxycarbonylethyl)-2,4-dimethylpyrrole-5-carboxylate 
• 67-56-1 methanol 
• 13984-53-7 methyl 4-acetyl-5-oxohexanoate 
• 27331-98-2 benzyl (Z/E)-2-hydroxyimino-3-oxobutanoate 
• 2386-37-0 ethyl 3,5-dimethyl-4-(2-methoxycarbonyl-ethyl)pyrrole-2-carboxylate 
• 5396-89-4 benzyl acetoacetate 
• 54278-10-3 ethyl 5-(ethoxycarbonyl)-2,4-dimethyl-1H-pyrrole-3-propanoate 
• 884336-84-9 4-(2-benzyloxycarbonylethyl)-3,5-dimethyl-1H-pyrrole-2-carboxylic acid ethyl ester 

Downstream Products

• 135363-65-4 Benzyl 4-(2-Methoxycarbonylethyl)-1,3,5-trimethylpyrrole-2-carboxylate 
• 16132-26-6 benzyl 4-(3-hydroxypropyl)-3,5-dimethyl-1H-pyrrole-2-carboxylate 
• 28844-01-1 benzyl 4-(2-hydrazidoethyl)-3,5-dimethylpyrrole-2-carboxylate 
• 75116-24-4 4-(2-Methoxycarbonyl-ethyl)-3-methyl-5-trichloromethyl-1H-pyrrole-2-carboxylic acid benzyl ester 
• 13219-76-6 4-<2-(methoxycarbonyl)ethyl>-3,5-dimethylpyrrole-2-carboxylic acid 
• 16258-78-9 Benzyl 2-formyl-3-<2-(methoxycarbonyl)ethyl>-4-methylpyrrole-5-carboxylate 
• 978-24-5 5-benzyloxycarbonyl-3-(2-methoxycarbonylethyl)-4-methylpyrrole-2-carboxylic acid 
• 63344-40-1 5-Hydroxymethyl-4-(2-methoxycarbonyl-ethyl)-3-methyl-1H-pyrrole-2-carboxylic acid benzyl ester 
• 992-36-9 dibenzyl 3,3'-bis(2-methoxycarbonylethyl)-4,4'-dimethyl-2,2'-pyrromethane-5,5'-dicarboxylate 
• 852160-79-3 4-(2-carboxyethyl)-3,5-dimethyl-1H-pyrrole-2-carboxylic acid benzyl ester 
• 164172-24-1 C₅₁H₆₂N₄O₉ 
• 164172-25-2 C₅₁H₆₂N₄O₉ 
• 256638-26-3 3-{5-(5-imino-3-methyl-4-vinyl-5H-furan-2-ylidenemethyl)-2-[5-iodo-3-(2-methoxycarbonyl-ethyl)-4-methyl-1H-pyrrol-2-ylmethylene]-4-methyl-2H-pyrrol-3-yl}-propionic acid methyl ester 
• 256638-23-0 3-{5-[(Z)-4-Carbamoyl-6-(4-chloro-phenylselanyl)-3-methyl-hex-3-en-1-ynyl]-2-[1-[5-iodo-3-(2-methoxycarbonyl-ethyl)-4-methyl-1H-pyrrol-2-yl]-meth-(Z)-ylidene]-4-methyl-2H-pyrrol-3-yl}-propionic acid methyl ester 

Relevant academic research and scientific papers

Corrole-Substituted Fluorescent Heme Proteins

Although fluorescent proteins have been utilized for a variety of biological applications, they have several optical limitations, namely weak red and near-infrared emission and exceptionally broad (>200 nm) emission profiles. The photophysical properties of fluorescent proteins can be enhanced through the incorporation of novel cofactors with the desired properties into a stable protein scaffold. To this end, a fluorescent phosphorus corrole that is structurally similar to the native heme cofactor is incorporated into two exceptionally stable heme proteins: H-NOX from Caldanaerobacter subterraneus and heme acquisition system protein A (HasA) from Pseudomonas aeruginosa. These yellow-orange emitting protein conjugates are examined by steady-state and time-resolved optical spectroscopy. The HasA conjugate exhibits enhanced fluorescence, whereas emission from the H-NOX conjugate is quenched relative to the free corrole. Despite the low fluorescence quantum yields, these corrole-substituted proteins exhibit more intense fluorescence in a narrower spectral profile than traditional fluorescent proteins that emit in the same spectral window. This study demonstrates that fluorescent corrole complexes are readily incorporated into heme proteins and provides an inroad for the development of novel fluorescent proteins.

Synthetic porphyrins bearing β-propionate chains as photosensitizers for photodynamic therapy

Porphyrins with different numbers of β-propionate chains mimicking natural porphyrins were prepared via the 2+2 MacDonald type approach. Photodynamic activity against WiDr colon adenocarcinoma cells showed that activity is related to the number of β-propi

Process For Preparing Porphyrin Derivatives, Such As Protoporphyrin (IX) And Synthesis Intermediates

The present invention relates to a process for preparing a porphyrin of formula (I), optionally in the form of a salt with an alkali metal and/or in the form of a metal complex: in which: R and R′ are as defined in claim 1, comprising: a step of condensation, in an acidic medium, between a dipyrromethane of formula (II): in which R′b is as defined above for (I), and a dipyrromethane of formula (III): in which R″ is as defined in claim 1, and also the compounds of formula (III).