20303-31-5

Basic information

• Product Name: METHYL 5-(BENZYLOXYCARBONYL)-2,4-DIMETHYL-3-PYRROLEPROPIONATE
• Synonyms: METHYL 5-(BENZYLOXYCARBONYL)-2,4-DIMETHYL-3-PYRROLEPROPIONATE;4-(2-METHOXYCARBONYL-ETHYL)-3,5-DIMETHYL-1H-PYRROLE-2-CARBOXYLIC ACID BENZYL ESTER;methyl 5-(benzyloxycarbonyl)dimethyl-3-pyrrolepropionate;Benzyl 4-(3-Methoxy-3-oxopropyl)-3,5-diMethyl-1H-pyrrole-2-carboxylate;Methyl 5-(benzyloxycarbonyl)-2,4-dimethyl-3-pyrrolepropionate 97%;Methyl 5-(benzyloxycarbonyl)-2,4-dimethyl-3-pyrrol;-3,5-dimethyl-1H-pyrrole-2-carboxylate;Benzyl 4-(3-methoxy-3-oxopropyl)
• CAS NO: 20303-31-5
• Molecular Formula: C₁₈H₂₁NO₄
• Molecular Weight: 315.36
• Product Categories: Building Blocks;Heterocyclic Building Blocks;Pyrroles;Building Blocks;Chemical Synthesis;Heterocyclic Building Blocks
• Mol File: 20303-31-5.mol
• Article Data: 3

Chemical Properties

• Melting Point: 98-99 °C(lit.)
• Boiling Point: 468.8°C at 760 mmHg
• Flash Point: 237.3°C
• Appearance: /
• Density: 1.175g/cm³
• Vapor Pressure: 5.82E-09mmHg at 25°C
• Refractive Index: 1.563
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 16.12±0.50(Predicted)
• CAS DataBase Reference: METHYL 5-(BENZYLOXYCARBONYL)-2,4-DIMETHYL-3-PYRROLEPROPIONATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 5-(BENZYLOXYCARBONYL)-2,4-DIMETHYL-3-PYRROLEPROPIONATE(20303-31-5)
• EPA Substance Registry System: METHYL 5-(BENZYLOXYCARBONYL)-2,4-DIMETHYL-3-PYRROLEPROPIONATE(20303-31-5)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39
• WGK Germany: 3
• Hazardous Substances Data: 20303-31-5(Hazardous Substances Data)

Usage

Uses

Methyl 5-(benzyloxycarbonyl)-2,4-dimethyl-3-pyrrolepropionate may be used in chemical synthesis studies.

InChI:InChI=1/C18H21NO4/c1-12-15(9-10-16(20)22-3)13(2)19-17(12)18(21)23-11-14-7-5-4-6-8-14/h4-8,19H,9-11H2,1-3H3

Upstream product

• 13984-53-7 methyl 4-acetyl-5-oxohexanoate 
• 27331-98-2 benzyl (Z/E)-2-hydroxyimino-3-oxobutanoate 
• 67-56-1 methanol 
• 99602-66-1 benzyl 3-(2-benzyloxycarbonylethyl)-2,4-dimethylpyrrole-5-carboxylate 
• 54278-10-3 ethyl 5-(ethoxycarbonyl)-2,4-dimethyl-1H-pyrrole-3-propanoate 
• 2386-37-0 ethyl 3,5-dimethyl-4-(2-methoxycarbonyl-ethyl)pyrrole-2-carboxylate 
• 5396-89-4 benzyl acetoacetate 
• 884336-84-9 4-(2-benzyloxycarbonylethyl)-3,5-dimethyl-1H-pyrrole-2-carboxylic acid ethyl ester 

Downstream Products

• 859-38-1 benzyl 5-acetoxymethyl-4-(2-methoxycarbonylethyl)-3-methylpyrrole-2-carboxylate 
• 26019-77-2 dibenzyl 3,7-Bis(2-methoxycarbonylethyl)-2,8-dimethyldipyrroketone-1,9-dicarboxylate 
• 499765-80-9 3,3'-bis-(2-methoxycarbonyl-ethyl)-4,4'-dimethyl-1H,1'H-[2,2']bipyrrolyl-5,5'-dicarboxylic acid dibenzyl ester 
• 850425-82-0 5-iodo-4-(2-methoxycarbonyl-ethyl)-3-methyl-pyrrole-1,2-dicarboxylic acid 2-benzyl ester 1-tert-butyl ester 
• 5594-29-6 3,3'-[7,12-bis-(1-hydroxy-ethyl)-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-diyl]-bis-propionic acid dimethyl ester 
• 5522-63-4 coproporphyrin III tetramethyl ester 
• 135363-72-3 Dibenzyl 3,3'-Bis(2-methoxycarbonylethyl)-1,4,4'-trimethyldipyrromethane-5,5'-dicarboxylate 
• 135363-66-5 Benzyl 5-Acetoxymethyl-4-(2-methoxycarbonylethyl)-1,3-dimethylpyrrole-2-carboxylate 
• 31837-46-4 tert-Butyl 5-(Benzyloxycarbonyl)-3-(2'-(methoxycarbonyl)ethyl)-4-methylpyrrole-2-carboxylate 
• 42419-16-9 tert-butyl 5'-(benzyloxycarbonyl)-3',4-bis(2-methoxycarbonylethyl)-3,4'-dimethyl-2,2'-dipyrrylmethane-5-carboxylate 
• 17484-82-1 benzyl 5-dimethylamido-3,4'-dimethyl-4,3'-bis(2'-methoxycarbonylethyl)-pyrromethane-5'-carboxylate 

Relevant articles and documents

-

-

Synthetic porphyrins bearing β-propionate chains as photosensitizers for photodynamic therapy

Porphyrins with different numbers of β-propionate chains mimicking natural porphyrins were prepared via the 2+2 MacDonald type approach. Photodynamic activity against WiDr colon adenocarcinoma cells showed that activity is related to the number of β-propi