2568-62-9Relevant academic research and scientific papers
Efficient ruthenium and copper cocatalzyed five-component coupling to form dipropargyl amines under mild conditions in water
Bonfield, E. Ryan,Li, Chao-Jun
, p. 435 - 437 (2007)
Dipropargyl amines are synthesized by a double direct alkynylation of primary followed by secondary imines formed in situ during an efficient, five-component, one-pot coupling reaction cocatalyzed by ruthenium and copper in water. The Royal Society of Che
Methods for Preparating Propargylamines through Metal-Free Decarboxylative Three-Component Coupling Reaction
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Paragraph 0142-0144, (2016/10/09)
The present invention relates to a method for producing propargylamine or derivatives thereof through a decarboxylative reaction without using a metal catalyst by making alkynyl carboxylic acid, aldehyde and amine react. According to the method of the pre
Metal-free decarboxylative three-component coupling reaction for the synthesis of propargylamines
Park, Kyungho,Heo, Yumi,Lee, Sunwoo
supporting information, p. 3322 - 3325 (2013/07/26)
A metal-free decarboxylative three-component coupling reaction was developed. When alkynyl carboxylic acids, paraformaldehyde, and amines were reacted in CH3CN at 65 °C for 3 h, the desired propargylamines were obtained in good yields. This coupling reaction also showed good yield in water solvent. This reaction showed higher selectivity toward alkynyl carboxylic acids than a terminal alkyne.
