25688-07-7

Upstream product

• 14673-56-4 acetone-4-phenylthiosemicarbazone 
• 29540-62-3 bis-(1-chloro-1-methyl-ethyl)-diazene 
• 103-72-0 phenyl isothiocyanate 

Downstream Products

• 87976-12-3 5,5-dimethyl-1,3-diphenyl-2-thioxoimidazolidin-4-one 
• 87976-11-2 4,4-dimethyl-1,3-diphenyl-5-thioxoimidazolidin-2-one 
• 80269-73-4 6-chloro-2,2-dimethyl-4-phenyl-1-thia-4-azaspiro<2.3>hexan-5-one 
• 87976-08-7 5-anilino-2,2,3-trimethyl-2,3-dihydro-1,3,4-thiadiazole 
• 21076-38-0 1-isopropyl-4-phenyl thiosemicarbazide 
• 80269-74-5 4-isopropylidene-2-oxo-1,3,3-triphenylazetidine 
• 80269-68-7 2,2-dimethyl-4,6,6-triphenyl-5-oxo-1-thia-4-azaspiro<2,3>hexane 

Relevant academic research and scientific papers

Synthesis, structure, and in vitro anti-HIV activity of new pyrazole, 1,2,4-thiadiazole, and 1,2,4-triazole derivatives

α,α'-Dichloroazo compounds 6 react with Lewis acid to furnish 1-(chloroalkyl)-1-aza-2-azoniaallene salts 4. The cations 4 react with acetylenes, isothiocyanates, isocyanates, and carbodiimides under [3+2]-cycloaddition. The cycloadducts undergo consecutiv

Synthesis and Some Reactions of 2-Imino-2,5-dihydro-1,3,4-thiadiazoles. Formation of β-Lactams

The title compounds, 2-imino-2,5-dihydro-1,3,4-thiadiazoles (2a-c), were prepared by oxidation of thiosemicarbazones.The reactions of (2a-c) with ketenes gave the spiro-β-lactams (7a-d), via cycloaddition.On the other hand, the reaction of (2a) with phenyl isocyanate gave the thiohydantoins (9) and (10).The reactions of compound (2) with some other nucleophiles are also described.