25688-10-2Relevant academic research and scientific papers
Synthesis and Some Reactions of 2-Imino-2,5-dihydro-1,3,4-thiadiazoles. Formation of β-Lactams
Yamamoto, Iwao,Abe, Ikuo,Nozawa, Muneharu,Kotani, Mitsuhiro,Motoyoshiya, Jiro,et al.
, p. 2297 - 2301 (2007/10/02)
The title compounds, 2-imino-2,5-dihydro-1,3,4-thiadiazoles (2a-c), were prepared by oxidation of thiosemicarbazones.The reactions of (2a-c) with ketenes gave the spiro-β-lactams (7a-d), via cycloaddition.On the other hand, the reaction of (2a) with phenyl isocyanate gave the thiohydantoins (9) and (10).The reactions of compound (2) with some other nucleophiles are also described.
