25688-46-4

Usage

Uses

Used in Coordination Chemistry:
Phosphine, tris[3-(trifluoromethyl)phenyl]is used as a ligand in coordination chemistry for the synthesis of transition metal complexes. These complexes are employed in various catalytic applications, making TFMP3 an essential component in the development of efficient and selective catalysts.
Used in Organic and Inorganic Reactions:
TFMP3 is utilized in various organic and inorganic reactions to facilitate the formation of chemical bonds. Its unique structure and properties enable it to act as a versatile reagent, promoting the synthesis of complex molecules and compounds.
Used in Pharmaceutical Industry:
Phosphine, tris[3-(trifluoromethyl)phenyl]has potential applications in the pharmaceutical industry. Its ability to form stable complexes with metal ions and its reactivity in organic reactions make it a promising candidate for the development of new drugs and pharmaceutical agents.
Used in Agrochemical Industry:
TFMP3 also has potential applications in the agrochemical industry. Its use in the synthesis of transition metal complexes and its reactivity in organic reactions can contribute to the development of new agrochemicals, such as pesticides and herbicides, with improved efficacy and selectivity.

Upstream product

• 401-81-0 m-trifluoromethylphenyl iodide 
• 401-78-5 3-bromo-1-trifluoromethylbenzene 

Downstream Products

• 207905-26-8 Fe(CO)4(P(C₆H₄CF₃)3) 
• 385815-85-0 (m-F₃CC₆H₄)3PAuSC₆H₅ 
• 385815-87-2 (m-F₃CC₆H₄)3PAuSC₅H₄N 
• 37095-25-3 [AuCl(P(3-CF₃-C₆H₄)3)] 
• 256418-56-1 HRh(CO)(P(C₆H₄-3-CF₃)3)3 
• 92451-54-2 cis-dichlorobis{tris(3-(trifluoromethyl)phenyl)phosphane}platinum(II) 
• 119907-96-9 methyltris<3-(trifluoromethyl)phenyl>phosphonium tosylate 
• 75619-33-9 Benzyltris-(m-trifluoromethylphenyl)phosphonium bromide 
• 74038-21-4 tris(3-(trifluoromethyl)phenyl)phosphine oxide 

Relevant academic research and scientific papers

Systematic Study of the Stereoelectronic Properties of Trifluoromethylated Triarylphosphines and the Correlation of their Behaviour as Ligands in the Rh-Catalysed Hydroformylation

The stereoelectronic properties of a series of trifluoromethylated aromatic phosphines have been studied using different approaches. The σ-donating capability has been evaluated by nuclear magnetic resonance (NMR) spectroscopy of the selenide derivatives and the protonated form of the different trifluoromethylated phosphines. The coupling constants between phosphorous and selenium (1JSeP) and phosphorous and hydrogen (1JHP) can be predicted by empirical equations and correlate the basicity of the phosphines with the number and relative position of trifluoromethyl groups. In contrast, the π-acceptor character of the ligands has been evaluated by measuring the frequency of the CO vibration in the infrared (IR) spectra of the corresponding Vaska type iridium complexes ([IrCl(CO)(PAr3)2], PAr3=triarylphosphine). Moreover, the correlation between the electronic properties and the performance of these phosphines as ligands in the rhodium-catalysed hydroformylation of 1-octene has been established. Phosphines with the lowest basicity, that are those with the highest number of trifluoromethyl groups, gave rise to more active catalytic systems.

Photocatalytic Arylation of P4 and PH3: Reaction Development Through Mechanistic Insight

Detailed 31P{1H} NMR spectroscopic investigations provide deeper insight into the complex, multi-step mechanisms involved in the recently reported photocatalytic arylation of white phosphorus (P4). Specifically, these studies have identified a number of previously unrecognized side products, which arise from an unexpected non-innocent behavior of the commonly employed terminal reductant Et3N. The different rate of formation of these products explains discrepancies in the performance of the two most effective catalysts, [Ir(dtbbpy)(ppy)2][PF6] (dtbbpy=4,4′-di-tert-butyl-2,2′-bipyridine) and 3DPAFIPN. Inspired by the observation of PH3 as a minor intermediate, we have developed the first catalytic procedure for the arylation of this key industrial compound. Similar to P4 arylation, this method affords valuable triarylphosphines or tetraarylphosphonium salts depending on the steric profile of the aryl substituents.

Syntheses and Spectroscopic Investigations of Substituted cis- and trans-Dichlorobis(triphenylphospane)platinum(II) Compounds

Compounds of the type cis- and trans-dichlorobis(triphenylphosphane)platinum(II) (3) with substituents of different electronic character in the phenyl rings bonded to phosphorus have been synthesized.The coupling constants 1J and the chloro-platinum valence vibrational frequencies are demonstrated to be criteria for unambiguous discrimination between cis- and trans-configurations at platinum; a linear correlation exists between the sum of the ?-constants of the sustituents at the triphenylphosphane and the coupling constants 1J.