256925-54-9

Upstream product

• 289039-29-8 2-chloro-5-iodobenzonitrile 
• 19094-56-5 2-chloro-5-iodobenzoic acid 
• 959909-89-8 2-chloro-5-iodo-N-methoxy-N-methylbenzamide 

Downstream Products

• 1035155-71-5 1-chloro-4-iodo-2-vinylbenzene 
• 1049811-60-0 benzyl-(2-chloro-5-iodo-benzyl)-amine 
• 1049811-59-7 2-(3-{4-Chloro-3-[(4-chloro-3-{[(phenylmethyl)amino]methyl}phenyl)ethynyl]phenyl}-1-{3-[(3S)-3-methylmorpholin-4-yl]propyl}-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridin-5-yl)-2-oxoacetamide 
• 1035155-79-3 ethyl 3-[4-chloro-3-((1S)-1-hydroxy-2-{[(4-methylphenyl)sulfonyl]oxy}ethyl)phenyl]propanoate 
• 1035155-75-9 ethyl (2E)-3-{4-chloro-3-[(1S)-1,2-dihydroxyethyl]phenyl}acrylate 
• 1035155-77-1 ethyl 3-{4-chloro-3-[(1S)-1,2-dihydroxyethyl]phenyl}propanoate 
• 1035155-81-7 ethyl 3-{4-chloro-3-[(2S)-oxiran-2-yl]phenyl}propanoate 
• 1035155-73-7 (1S)-1-(2-chloro-5-iodophenyl)ethane-1,2-diol 

Relevant academic research and scientific papers

NON-CYCLIC SUBSTITUTED BENZIMIDAZOLE THIOPHENE BENZYL ETHER COMPOUNDS

The present invention provides benzimidazole thiophene compounds pharmaceutical compositions containing the same, processes for preparing the same and their use as pharmaceutical agents.

CARBON-LINKED TETRAHYDRO-PYRAZOLO-PYRIDINE MODULATORS OF CATHEPSIN S

Carbon-linked tetrahydro-pyrazolo-pyridine compounds are described, which are useful as cathepsin S modulators. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by cathepsin S activity, such as psoriasis, pain, multiple sclerosis, atherosclerosis, and rheumatoid arthritis.

CALCILYTIC COMPOUNDS

Novel calcilytic compounds, pharmaceutical compositions, methods of synthesis and methods of using them are provided.

Survivin inhibitors

Compounds that inhibit survivin, compositions containing the compounds and methods of treating diseases in which survivin is unregulated or overexpressed are disclosed.