25699-91-6

Upstream product

• 120-72-9 indole 
• 403-54-3 m-Fluorobenzonitrile 
• 766-84-7 3-chloro-benzonitrile 

Downstream Products

• 92083-34-6 1-(3-aminomethylphenyl)indole 
• 128742-81-4 3-{3-[4-(1-Methyl-1H-indol-3-yl)-2,5-dioxo-2,5-dihydro-furan-3-yl]-indol-1-yl}-benzonitrile 
• 92083-35-7 3-(1-indolyl)benzenemethanamine hydrochloride 

Relevant academic research and scientific papers

A novel and selective method for the N-arylation of indoles mediated by KF/Al2O3

Indole was reacted with aryl electrophiles in the presence of 37% KF/Al2O3 and catalytic 18-crown-6 in DMSO at 120°C to give selectively 1-arylindoles in fair to excellent yield. Electrophiles containing electronically unfavorable su

Method for arylating aza-heterocycles with activated aromatic compounds in the presence of caesium carbonate

The invention concerns a process for the preparation of N-aryl-aza-heterocycles of the general formula I by reaction of aza-heterocycles with activated aryl halides with use of caesium carbonate without addition of further catalysts at room temperature.

3-(1-Indolinyl)benzylamines: A New Class of Analgesic Agents

An extensive series of 3-(1-indolinyl)benzylamines and related compounds was sunthesized and tested for analgesic activity.After a detailed study of structure-activity relationships, 3-(1-indolinyl)benzylamine (2b) was selected for further investigation a

1-(Aminoalkylphenyl and aminoalkylbenzyl)-indoles and indolines and analgesic method of use thereof

The invention relates to 1-(aminoalkylphenyl and aminoalkylbenzyl)indoles and indolines of the formula: STR1 where R1 and R2 are the same or different and are hydrogen, lower alkyl, cycloalkyl and acyl of the formula STR2 where Rsub