92083-34-6Relevant academic research and scientific papers
The copper-catalyzed N-arylation of indoles
Antilla, Jon C.,Klapars, Artis,Buchwald, Stephen L.
, p. 11684 - 11688 (2007/10/03)
A general method for the N-arylation of indoles using catalysts derived from Cul and trans-1,2-cyclohexanediamine (1a), trans-N,N′-dimethyl-1,2-cyclohexanediamine (2a), or N,N′-dimethyl-ethylenediamine (3) is reported. N-Arylindoles can be produced in high yield from the coupling of an aryl iodide or aryl bromide with a variety of indoles.
3-(1-Indolinyl)benzylamines: A New Class of Analgesic Agents
Glamkowski, Edward J.,Fortunato, James M.,Spaulding, Theodore C.,Wilker, Jeffrey C.,Ellis, Daniel B.
, p. 66 - 73 (2007/10/02)
An extensive series of 3-(1-indolinyl)benzylamines and related compounds was sunthesized and tested for analgesic activity.After a detailed study of structure-activity relationships, 3-(1-indolinyl)benzylamine (2b) was selected for further investigation a
