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2,6-dimethylfuro[2,3-d]pyrimidin-4(3H)-one is a heterocyclic compound characterized by a fused furan and pyrimidine ring structure. It is recognized for its potential medicinal properties and biological activities, which include antitumor, anti-inflammatory, and antimicrobial effects. 2,6-dimethylfuro[2,3-d]pyrimidin-4(3H)-one is a versatile building block in the synthesis of various pharmaceutical drugs, agrochemicals, dyes, and other organic compounds, making it a significant player in the fields of medicinal and organic chemistry.

25716-54-5

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25716-54-5 Usage

Uses

Used in Pharmaceutical Industry:
2,6-dimethylfuro[2,3-d]pyrimidin-4(3H)-one is used as a key intermediate in the synthesis of various pharmaceutical drugs. Its unique structure and potential medicinal properties contribute to the development of new therapeutic agents.
Used in Agrochemical Production:
2,6-dimethylfuro[2,3-d]pyrimidin-4(3H)-one is utilized as a building block in the production of agrochemicals, where its chemical properties can be harnessed to create effective products for agricultural applications.
Used in Dye Manufacturing:
2,6-dimethylfuro[2,3-d]pyrimidin-4(3H)-one is employed in the manufacturing of dyes, where its structural characteristics are leveraged to produce a range of colorants for various industries.
Used in Organic Chemistry Research:
2,6-dimethylfuro[2,3-d]pyrimidin-4(3H)-one serves as an important chemical entity in the field of organic chemistry, where it is used in research and development to explore new synthetic pathways and applications.

Check Digit Verification of cas no

The CAS Registry Mumber 25716-54-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,5,7,1 and 6 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 25716-54:
(7*2)+(6*5)+(5*7)+(4*1)+(3*6)+(2*5)+(1*4)=115
115 % 10 = 5
So 25716-54-5 is a valid CAS Registry Number.

25716-54-5Relevant academic research and scientific papers

BAX INHIBITORS AND USES THEREOF

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Paragraph 00440, (2021/01/23)

A compound having formula (I) or (II) for use inhibiting Bax mediated cell death and/or apoptosis.

RADIOLABELED MICROTUBULE IMAGING COMPOUNDS AND USES THEREOF

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, (2019/05/22)

The present disclosure relates to radiolabeled compounds and methods of uses for diagnosis, monitoring, and treatment of various degenerative neurological disorders, neuropsychiatric disorders, brain injuries, vascular diseases, and cancers. Radiolabeled compounds for imaging of microtubules or microtubules and other targets using positron-emission tomography (PET) are specifically disclosed.

CONFORMATIONALLY RESTRICTED 4-SUBSTITUTED-2,6-DIMETHYLFURO[2,3-d]PYRIMIDINES AS ANTITUMOR AGENTS

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, (2016/07/05)

The present invention provides conformationally restricted 4-substituted 2,6-dimethylfuro[2,3-d]pyrimidine compounds and pharmaceutical compositions comprising these compounds. Preferably, the compounds exhibit dual inhibition of microtubule assembly and

The design and discovery of water soluble 4-substituted-2,6-dimethylfuro[2, 3-d]pyrimidines as multitargeted receptor tyrosine kinase inhibitors and microtubule targeting antitumor agents

Zhang, Xin,Raghavan, Sudhir,Ihnat, Michael,Thorpe, Jessica E.,Disch, Bryan C.,Bastian, Anja,Bailey-Downs, Lora C.,Dybdal-Hargreaves, Nicholas F.,Rohena, Cristina C.,Hamel, Ernest,Mooberry, Susan L.,Gangjee, Aleem

, p. 3753 - 3772 (2014/07/07)

The design, synthesis and biological evaluations of fourteen 4-substituted 2,6-dimethylfuro[2,3-d]pyrimidines are reported. Four compounds (11-13, 15) inhibit vascular endothelial growth factor receptor-2 (VEGFR-2), platelet-derived growth factor receptor

BICYCLIC AND TRICYCLIC PYRIMIDINE TYROSINE KINASE INHIBITORS WITH ANTITUBULIN ACTIVITY AND METHODS OF TREATING A PATIENT

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Page/Page column 63, (2012/08/27)

Bicyclic and tricyclic pyrimidine tyrosine kinase inhibitors with antitubulin activity are provided in the present invention. The compositions of the present invention possess dual activity in a single agent of potent vascular endothelial growth factor re

BICYCLIC COMPOUNDS HAVING ANTIMITOTIC AND/OR ANTITUMOR ACTIVITY AND METHODS OF USE THEREOF

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Page/Page column 10-11, (2010/02/17)

The present invention provides bicyclic compounds, pharmaceutically acceptable salts, prodrugs, solvates, and hydrates thereof, having antimitotic activity, anti-multidrug resistance activity, such as for example P-glycoprotein inhibition, and antitumor a

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