25728-82-9Relevant articles and documents
Synthesis of even C24-C30 primary normal aliphatic alcohols from cyclododecanone
Zakharkin, L. I.,Churilova, I. M.,Anikina, E. V.
, p. 65 - 67 (2007/10/02)
A simple method has been developed for the oxidation of cyclododecanone by sodium persulfate in an aqueous methanol solution of sulfuric acid to give 12-hydroxydodecanoic acid, which upon treatment with HBr in acetic acid gives 12-bromododecanoic acid with RMgX, where R=C12H25, C14H29, C16H33, and C18H37 in THF in the presence of Li2CuCl4 and subsequent reduction of the salts of the alkanecarboxylic acids by LiAlH4 give primary even normal C24-C30 alcohols.
