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Policosanol
Cas No: 557-61-9
USD $ 38.0-38.0 / Kilogram 1 Kilogram 500 Kilogram/Month Greenutra Resource Inc Contact Supplier
Factory Policosanol Octacosanol Powder 60% 90% 98%
Cas No: 557-61-9
USD $ 100.0-100.0 / Kilogram 1 Kilogram 1000 Kilogram/Month Shaanxi Yuantai Biological Technology Co., Ltd. Contact Supplier
Sugar Cane Wax Extract/Rice Bran Wax Extract Octacosanol Policosanol
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USD $ 50.0-50.0 / Kilogram 1 Kilogram 1000 Kilogram/Month Purestar Chem Enterprise Co.,Ltd Contact Supplier
Top Quality Octacosanol
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USD $ 1.0-1.0 / Kilogram 1 Kilogram 100 Metric Ton/Month Salus Nutra Inc Contact Supplier
1-Octacosanol
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USD $ 3.0-3.0 / Kilogram 1 Kilogram 1-100 Metric Ton/Month Dayang Chem (Hangzhou) Co.,Ltd. Contact Supplier
High quality 1-Octacosanol supplier in China
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No Data 1 Kilogram 30 Metric Ton/Month Simagchem Corporation Contact Supplier
Octacosanol 98% Sugarcane Extract powder
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USD $ 10.0-100.0 / Kilogram 1 Kilogram 5000 Kilogram/Month Kono Chem Co.,Ltd Contact Supplier
1-Octacosanol CAS NO.557-61-9
Cas No: 557-61-9
USD $ 2.0-2.0 / Gram 100 Gram 100 Metric Ton/Month Hebei yanxi chemical co.,LTD. Contact Supplier
High Quality Oled CAS 557-61-9 1-Octacosanol
Cas No: 557-61-9
USD $ 0.1-0.1 / Gram 1 Gram 100 Metric Ton/Year Xi'an Xszo Chem Co., Ltd. Contact Supplier
Factory Supply high qualtiy 1-Octacosanol
Cas No: 557-61-9
No Data 1 1 Ality Chemical Corporation Contact Supplier

557-61-9 Usage

Reactivity Profile

1-Octacosanol is an alcohol. Flammable and/or toxic gases are generated by the combination of alcohols with alkali metals, nitrides, and strong reducing agents. They react with oxoacids and carboxylic acids to form esters plus water. Oxidizing agents convert them to aldehydes or ketones. Alcohols exhibit both weak acid and weak base behavior. They may initiate the polymerization of isocyanates and epoxides.

Occurrence

Octacosanol is developed from wheat germ, sugar cane, or vegetable waxes.

Air & Water Reactions

Insoluble in water.

Chemical Properties

white crystals or powder

Purification Methods

Recrystallise it from large volumes of Me2CO. Sublime it at 200-250o/1mm instead of distilling it. [Beilstein 2 IV 1318.]

Definition

ChEBI: A long-chain primary fatty alcohol that is octacosane in which a hydrogen attached to one of the terminal carbons is replaced by a hydroxy group.

Fire Hazard

Flash point data for 1-Octacosanol are not available; however, 1-Octacosanol is probably combustible.

General Description

White crystalline powder.

Uses

A 28-carbon primary fatty alcohol commonly found in the epicuticular waxes of plants. It has shown protective effects against parkonsonism and due to its excellent tolerability and non-toxicity, octacosanol may be a promising agent for PD treatment.
InChI:InChI=1/C28H58O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24-25-26-27-28-29/h29H,2-28H2,1H3

557-61-9 Well-known Company Product Price

Brand (Code)Product description CAS number Packaging Price Detail
Sigma (O3379)  1-Octacosanol  ≥99% (GC) 557-61-9 O3379-100MG 638.82CNY Detail
Sigma (O3379)  1-Octacosanol  ≥99% (GC) 557-61-9 O3379-500MG 2,688.66CNY Detail
Sigma (O3379)  1-Octacosanol  ≥99% (GC) 557-61-9 O3379-1G 5,308.29CNY Detail

557-61-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name octacosan-1-ol

1.2 Other means of identification

Product number -
Other names N-OCTACOSANOL

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:557-61-9 SDS

557-61-9Synthetic route

(E,Z)-octacos-10-en-1-ol
636583-59-0

(E,Z)-octacos-10-en-1-ol

octacosyl alcohol
557-61-9

octacosyl alcohol

Conditions
ConditionsYield
With hydrogen; palladium on activated charcoal In methanol under 19001.3 Torr; for 6h;97%
With palladium 10% on activated carbon; hydrogen In tetrahydrofuran at 80℃; under 26252.6 Torr; for 4h;89%
benzyl 1-octacosanol

benzyl 1-octacosanol

octacosyl alcohol
557-61-9

octacosyl alcohol

Conditions
ConditionsYield
With hydrogen; 5%-palladium/activated carbon In propan-1-ol at 90℃; under 3750.38 Torr; for 18h;81%
benzyl octacos-10-enol

benzyl octacos-10-enol

octacosyl alcohol
557-61-9

octacosyl alcohol

Conditions
ConditionsYield
With hydrogen; 5%-palladium/activated carbon In propan-1-ol at 90℃; under 3750.38 Torr; for 18h;80%
2-octacosyloxy-tetrahydro-pyran

2-octacosyloxy-tetrahydro-pyran

octacosyl alcohol
557-61-9

octacosyl alcohol

Conditions
ConditionsYield
With hydrogenchloride; acetic acid In tetrahydrofuran; ethanol; water at 20℃; for 16h;80%
t-butyl-dimethyl-octacosyloxy-silane

t-butyl-dimethyl-octacosyloxy-silane

octacosyl alcohol
557-61-9

octacosyl alcohol

Conditions
ConditionsYield
With hydrogenchloride In ethanol at 72℃; for 5h;77%
icosane
112-95-8

icosane

n-docosane
629-97-0

n-docosane

n-hexacosane
630-01-3

n-hexacosane

Tridecane
629-50-5

Tridecane

octadecane
593-45-3

octadecane

tetracosane
646-31-1

tetracosane

octacosane
630-02-4

octacosane

n-triacontane
638-68-6

n-triacontane

A

1-octadecanol
112-92-5

1-octadecanol

B

n-eicosanol
629-96-9

n-eicosanol

C

melissyl alcohol
593-50-0

melissyl alcohol

D

1-docosanol
661-19-8

1-docosanol

E

tetracosyl alcohol
506-51-4

tetracosyl alcohol

F

hexacosyl alcohol
506-52-5

hexacosyl alcohol

G

octacosyl alcohol
557-61-9

octacosyl alcohol

Conditions
ConditionsYield
Stage #1: icosane; n-docosane; n-hexacosane; octadecane; tetracosane; octacosane; n-triacontane With oxygen at 30 - 50℃; under 1575.16 Torr; for 0.5h;
Stage #2: Tridecane With titanium(IV) isopropylate at 30 - 50℃; under 1575.16 - 3750.38 Torr; for 6.86667h;
Stage #3: With sulfuric acid; water at 80℃; Product distribution / selectivity;
A 17.66%
B 19.46%
C 0.1%
D 13.62%
E 6.93%
F 2.04%
G 0.48%
icosane
112-95-8

icosane

n-docosane
629-97-0

n-docosane

n-hexacosane
630-01-3

n-hexacosane

octadecane
593-45-3

octadecane

tetracosane
646-31-1

tetracosane

octacosane
630-02-4

octacosane

n-triacontane
638-68-6

n-triacontane

A

1-octadecanol
112-92-5

1-octadecanol

B

n-eicosanol
629-96-9

n-eicosanol

C

melissyl alcohol
593-50-0

melissyl alcohol

D

1-docosanol
661-19-8

1-docosanol

E

tetracosyl alcohol
506-51-4

tetracosyl alcohol

F

hexacosyl alcohol
506-52-5

hexacosyl alcohol

G

octacosyl alcohol
557-61-9

octacosyl alcohol

Conditions
ConditionsYield
Stage #1: icosane; n-docosane; n-hexacosane; octadecane; tetracosane; octacosane; n-triacontane With oxygen at 30 - 50℃; under 1575.16 - 3675.37 Torr; for 3h;
Stage #2: With sulfuric acid; water Product distribution / selectivity;
A 12.4%
B 13.4%
C 0.05%
D 7.8%
E 3.2%
F 1%
G 0.2%
ethyl octacosanoate
6624-78-8

ethyl octacosanoate

octacosyl alcohol
557-61-9

octacosyl alcohol

Conditions
ConditionsYield
With sodium; Petroleum ether; butan-1-ol
With lithium aluminium tetrahydride
methyl octacosanoate
55682-92-3

methyl octacosanoate

octacosyl alcohol
557-61-9

octacosyl alcohol

Conditions
ConditionsYield
With lithium aluminium tetrahydride In tetrahydrofuran for 1h; Heating;
sodium octacosanoate
25728-82-9

sodium octacosanoate

octacosyl alcohol
557-61-9

octacosyl alcohol

Conditions
ConditionsYield
With lithium aluminium tetrahydride In tetrahydrofuran Heating; Yield given;
Octacos-9-yn-1-ol
148172-69-4

Octacos-9-yn-1-ol

octacosyl alcohol
557-61-9

octacosyl alcohol

Conditions
ConditionsYield
With hydrogen; palladium on activated charcoal In ethanol
Erythrinasinate

Erythrinasinate

A

octacosyl alcohol
557-61-9

octacosyl alcohol

B

trans-3-hydroxy-4-methoxycinnamic acid
537-73-5

trans-3-hydroxy-4-methoxycinnamic acid

Conditions
ConditionsYield
With potassium hydroxide In chloroform for 1h; Heating;A 50 mg
B 8 mg
octacosanyl triacontanoate

octacosanyl triacontanoate

A

octacosyl alcohol
557-61-9

octacosyl alcohol

B

melissic acid
506-50-3

melissic acid

Conditions
ConditionsYield
With potassium hydroxide In ethanol for 5h; Heating;
(2R,3S,4S,5R,6R)-2-Hydroxymethyl-6-octacosyloxy-tetrahydro-pyran-3,4,5-triol

(2R,3S,4S,5R,6R)-2-Hydroxymethyl-6-octacosyloxy-tetrahydro-pyran-3,4,5-triol

octacosyl alcohol
557-61-9

octacosyl alcohol

Conditions
ConditionsYield
With hydrogenchloride In methanol for 5h; Heating;
Benzoic acid (2R,3R,4S,5R,6R)-3,5-dihydroxy-2-hydroxymethyl-6-octacosyloxy-tetrahydro-pyran-4-yl ester

Benzoic acid (2R,3R,4S,5R,6R)-3,5-dihydroxy-2-hydroxymethyl-6-octacosyloxy-tetrahydro-pyran-4-yl ester

octacosyl alcohol
557-61-9

octacosyl alcohol

Conditions
ConditionsYield
With hydrogenchloride In methanol for 5h; Heating;
Multi-step reaction with 2 steps
1: KOH / methanol / 5 h / Heating
2: HCl / methanol / 5 h / Heating
View Scheme
12-hydroxydodecanoic acid
505-95-3

12-hydroxydodecanoic acid

octacosyl alcohol
557-61-9

octacosyl alcohol

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 90 percent / 50percent HBr / acetic acid / 5 h / Heating
2: EtONa / ethanol / 0.5 h / Heating
3: Li2CuCl4 / tetrahydrofuran / 4 h / -10 - -5 °C
4: LiAlH4 / tetrahydrofuran / Heating
View Scheme
12-bromododecanoic acid
73367-80-3

12-bromododecanoic acid

octacosyl alcohol
557-61-9

octacosyl alcohol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: EtONa / ethanol / 0.5 h / Heating
2: Li2CuCl4 / tetrahydrofuran / 4 h / -10 - -5 °C
3: LiAlH4 / tetrahydrofuran / Heating
View Scheme
octacosyl alcohol

octacosyl alcohol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: Li2CuCl4 / tetrahydrofuran / 4 h / -10 - -5 °C
2: LiAlH4 / tetrahydrofuran / Heating
View Scheme
9-decyn-1-ol
17643-36-6

9-decyn-1-ol

octacosyl alcohol
557-61-9

octacosyl alcohol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 1.) n-BuLi / 1.) HMPA. 2.) HMPA
2: H2 / Pd/C / ethanol
View Scheme
1-Bromooctadecane
112-89-0

1-Bromooctadecane

octacosyl alcohol
557-61-9

octacosyl alcohol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 1.) n-BuLi / 1.) HMPA. 2.) HMPA
2: H2 / Pd/C / ethanol
View Scheme
methyl adipoyl chloride
35444-44-1

methyl adipoyl chloride

octacosyl alcohol
557-61-9

octacosyl alcohol

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 65 percent / stannic chloride / benzene / 2 h / Ambient temperature
2: BF3(OC2H5)3 / CHCl3 / Ambient temperature
3: W6 Raney nickel / ethanol / Heating
4: LAH / tetrahydrofuran / 1 h / Heating
View Scheme
2-octadecylthiophene
102945-07-3

2-octadecylthiophene

octacosyl alcohol
557-61-9

octacosyl alcohol

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 65 percent / stannic chloride / benzene / 2 h / Ambient temperature
2: BF3(OC2H5)3 / CHCl3 / Ambient temperature
3: W6 Raney nickel / ethanol / Heating
4: LAH / tetrahydrofuran / 1 h / Heating
View Scheme
6-(5-Octadecyl-thiophen-2-yl)-6-oxo-hexanoic acid methyl ester
111514-85-3

6-(5-Octadecyl-thiophen-2-yl)-6-oxo-hexanoic acid methyl ester

octacosyl alcohol
557-61-9

octacosyl alcohol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: BF3(OC2H5)3 / CHCl3 / Ambient temperature
2: W6 Raney nickel / ethanol / Heating
3: LAH / tetrahydrofuran / 1 h / Heating
View Scheme
5-[2-(5-Octadecyl-thiophen-2-yl)-[1,3]dithiolan-2-yl]-pentanoic acid methyl ester
111514-96-6

5-[2-(5-Octadecyl-thiophen-2-yl)-[1,3]dithiolan-2-yl]-pentanoic acid methyl ester

octacosyl alcohol
557-61-9

octacosyl alcohol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: W6 Raney nickel / ethanol / Heating
2: LAH / tetrahydrofuran / 1 h / Heating
View Scheme
C30H62O2

C30H62O2

octacosyl alcohol
557-61-9

octacosyl alcohol

Conditions
ConditionsYield
With methanol; hydrogenchloride Heating / reflux;
With methanol; hydrogenchloride Heating / reflux;
BrMg(1+)*C10H20BrO(1-)

BrMg(1+)*C10H20BrO(1-)

n-octadecylmagnesium chloride

n-octadecylmagnesium chloride

octacosyl alcohol
557-61-9

octacosyl alcohol

Conditions
ConditionsYield
Stage #1: BrMg(1+)*C10H20BrO(1-); dilithium tetrachlorocuprate In tetrahydrofuran at -20℃; for 0.333333h;
Stage #2: n-octadecylmagnesium chloride In tetrahydrofuran at -20 - 20℃;
Stage #3: With ammonium chloride In tetrahydrofuran; water
1-Bromo-11-hydroxyundecane
1611-56-9

1-Bromo-11-hydroxyundecane

octacosyl alcohol
557-61-9

octacosyl alcohol

Conditions
ConditionsYield
Multi-step reaction with 7 steps
1: triethylamine / dichloromethane
2: n-butyllithium; N,N,N,N,N,N-hexamethylphosphoric triamide / tetrahydrofuran
3: hydrogen; palladium 10% on activated carbon / ethyl acetate
4: pyridinium chlorochromate / dichloromethane
5: sodium hexamethyldisilazane / tetrahydrofuran
6: tetrabutyl ammonium fluoride / tetrahydrofuran
7: hydrogen; palladium 10% on activated carbon / ethyl acetate
View Scheme
(11-bromoundecyloxy)(tert-butyl)diphenylsilane
172995-51-6

(11-bromoundecyloxy)(tert-butyl)diphenylsilane

octacosyl alcohol
557-61-9

octacosyl alcohol

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: n-butyllithium; N,N,N,N,N,N-hexamethylphosphoric triamide / tetrahydrofuran
2: hydrogen; palladium 10% on activated carbon / ethyl acetate
3: pyridinium chlorochromate / dichloromethane
4: sodium hexamethyldisilazane / tetrahydrofuran
5: tetrabutyl ammonium fluoride / tetrahydrofuran
6: hydrogen; palladium 10% on activated carbon / ethyl acetate
View Scheme
C30H44O2Si
1538660-98-8

C30H44O2Si

octacosyl alcohol
557-61-9

octacosyl alcohol

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: hydrogen; palladium 10% on activated carbon / ethyl acetate
2: pyridinium chlorochromate / dichloromethane
3: sodium hexamethyldisilazane / tetrahydrofuran
4: tetrabutyl ammonium fluoride / tetrahydrofuran
5: hydrogen; palladium 10% on activated carbon / ethyl acetate
View Scheme
octacosyl alcohol
557-61-9

octacosyl alcohol

methanesulfonyl chloride
124-63-0

methanesulfonyl chloride

C29H60O3S

C29H60O3S

Conditions
ConditionsYield
With triethylamine In tetrahydrofuran at 80℃;70%
octacosyl alcohol
557-61-9

octacosyl alcohol

octacosanal aldehyde
22725-64-0

octacosanal aldehyde

Conditions
ConditionsYield
Stage #1: octacosyl alcohol With calcium carbonate In dichloromethane at 20℃; for 0.5h; Molecular sieves (MS4A);
Stage #2: With pyridinium chlorochromate In dichloromethane at 20℃; for 2h;
Stage #3: In hexane; dichloromethane for 0.25h;
45.9%
With pyridinium chlorochromate Oxidation;
octacosyl alcohol
557-61-9

octacosyl alcohol

octacosanol iodide
62154-80-7

octacosanol iodide

Conditions
ConditionsYield
With phosphorus; iodine
octacosyl alcohol
557-61-9

octacosyl alcohol

octacosanoic acid
506-48-9

octacosanoic acid

Conditions
ConditionsYield
With chromium; acetic acid
Jones Oxidation;
octacosyl alcohol
557-61-9

octacosyl alcohol

acetic anhydride
108-24-7

acetic anhydride

octacosanol acetate
18206-97-8

octacosanol acetate

Conditions
ConditionsYield
With sodium acetate
With pyridine
In pyridine
octacosyl alcohol
557-61-9

octacosyl alcohol

allylisocyanate
1476-23-9

allylisocyanate

allyl-carbamic acid octacosyl ester
121706-85-2

allyl-carbamic acid octacosyl ester

Conditions
ConditionsYield
With benzene
octacosyl alcohol
557-61-9

octacosyl alcohol

(E)-3-<3-Methoxy-4-(tetrahydropyran-2-yloxy)phenyl>prop-2-enoic acid
145205-03-4

(E)-3-<3-Methoxy-4-(tetrahydropyran-2-yloxy)phenyl>prop-2-enoic acid

(E)-3-[3-Methoxy-4-(tetrahydro-pyran-2-yloxy)-phenyl]-acrylic acid octacosyl ester

(E)-3-[3-Methoxy-4-(tetrahydro-pyran-2-yloxy)-phenyl]-acrylic acid octacosyl ester

Conditions
ConditionsYield
With dicyclohexyl-carbodiimide In pyridine at 50 - 55℃;
octacosyl alcohol
557-61-9

octacosyl alcohol

1-bromo-octacosane
16331-21-8

1-bromo-octacosane

Conditions
ConditionsYield
With sulfuric acid; hydrogen bromide at 90 - 110℃;
octacosyl alcohol
557-61-9

octacosyl alcohol

oleoyl chloride

oleoyl chloride

octacosyl oleate

octacosyl oleate

Conditions
ConditionsYield
With pyridine In tetrachloromethane Ambient temperature;
octacosyl alcohol
557-61-9

octacosyl alcohol

n-hexadecanoyl chloride
112-67-4

n-hexadecanoyl chloride

octacosanyl hexadecanoate

octacosanyl hexadecanoate

Conditions
ConditionsYield
With pyridine In tetrachloromethane Ambient temperature;

557-61-9Downstream Products

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