257280-25-4

Basic information

• Product Name: 5-BROMO-2-PHENOXYPYRIMIDINE
• Synonyms: 5-BROMO-2-PHENOXYPYRIMIDINE
• CAS NO: 257280-25-4
• Molecular Formula: C₁₀H₇BrN₂O
• Molecular Weight: 251.08
• EINECS: 1312995-182-4
• Product Categories: Heterocycle-Pyrimidine series
• Mol File: 257280-25-4.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 366.7 °C at 760 mmHg
• Flash Point: 175.6 °C
• Appearance: /
• Density: 1.543 g/cm³
• Vapor Pressure: 3.02E-05mmHg at 25°C
• Refractive Index: 1.612
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 5-BROMO-2-PHENOXYPYRIMIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-BROMO-2-PHENOXYPYRIMIDINE(257280-25-4)
• EPA Substance Registry System: 5-BROMO-2-PHENOXYPYRIMIDINE(257280-25-4)

Safety Data

• Statements: 43
• Safety Statements: 36/37
• Hazardous Substances Data: 257280-25-4(Hazardous Substances Data)

Usage

General Description

5-Bromo-2-phenoxy-pyrimidine is a chemical compound with the molecular formula C11H8BrN3O. It is a pyrimidine derivative with a bromine atom and a phenoxy group attached to the pyrimidine ring. 5-BROMO-2-PHENOXYPYRIMIDINE is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It is also used as a building block in the production of various organic compounds. 5-Bromo-2-phenoxy-pyrimidine is a white to off-white solid that is sparingly soluble in water but soluble in organic solvents. It has potential applications in the pharmaceutical and agricultural industries due to its ability to modify and enhance biological activity.

InChI:InChI=1/C10H7BrN2O/c11-8-6-12-10(13-7-8)14-9-4-2-1-3-5-9/h1-7H

Upstream product

• 38353-06-9 5-bromopyrimidin-2-ol 
• 66003-76-7 Diphenyliodonium triflate 
• 32779-36-5 5-Bromo-2-chloropyrimidine 
• 108-95-2 phenol 
• 183438-24-6 5-bromo-2-iodopyrimidine 
• 98-80-6 phenylboronic acid 

Downstream Products

• 1254171-30-6 5-(trimethylstannyl)-2-phenoxypyrimidine 
• 330792-85-3 2-phenoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine 

Relevant articles and documents

Method of preparing Quinoline-5,8-dione derivatives for TGase 2 inhibitor

I Is -5,8- of the quinoline, dione derivative compound. of Formula I, or a stereoisomer or a pharmaceutically acceptable salt thereof, wherein the compound of Formula, TGase 2 has, inhibitory effects TGase 2, and thus the pharmaceutical composition may be useful for preventing or treating disorders or diseases mediated by TGase 2 or inhibiting. (by machine translation)

BTK INHIBITOR COMPOUNDS

The invention provides BTK Inhibitor compounds, pharmaceutically acceptable salts, pharmaceutical compositions thereof, and methods of using these compounds, salts, or compositions to treat autoimmune diseases such as Rheumatoid Arthritis.

Quinoline-5,8-dione derivatives for TGase 2 inhibitor, and the pharmaceutical composition comprising the same

The present invention relates to a quinolin-5,8-dione derivative compound represented by chemical formula I, an optical isomer thereof or a pharmaceutically acceptable salt thereof. The compound represented by chemical formula I of the present invention has a TGase 2 inhibitory effect, and the pharmaceutical composition comprising the same can be usefully used for preventing or treating disorders or diseases mediated by TGase 2 or response to TGase 2 inhibition.COPYRIGHT KIPO 2020