25761-73-3Relevant academic research and scientific papers
Iridium-catalyzed annulation of N -arylcarbamoyl chlorides with internal alkynes
Iwai, Tomohiro,Fujihara, Tetsuaki,Terao, Jun,Tsuji, Yasushi
supporting information; experimental part, p. 9602 - 9603 (2010/08/22)
An iridium complex successfully catalyzed the annulation of various N-arylcarbamoyl chlorides with internal alkynes to afford 2-quinolones in good to excellent yields. The present reaction is widely applicable to substrates with various functionalities. An amide-iridacycle complex was isolated, and it is likely that such an iridacycle species is a key intermediate in the catalytic reaction.
