25769-61-3 Usage
Uses
Glycolic Anhydride Diacetate, is the product of reaction involving Lead tetraacetate as an oxidizing agent It is also an intermediate in the synthesis of Chrysogine, a metabolite of Penicillium chrysogenum and some related 2-substituted 4-(3H)-quinazolinones.
Check Digit Verification of cas no
The CAS Registry Mumber 25769-61-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,5,7,6 and 9 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 25769-61:
(7*2)+(6*5)+(5*7)+(4*6)+(3*9)+(2*6)+(1*1)=143
143 % 10 = 3
So 25769-61-3 is a valid CAS Registry Number.
25769-61-3Relevant articles and documents
Pyridylmethylthio derivatives as VEGF inhibitors: Part 2
Tajima, Hisashi,Honda, Takahiro,Kawashima, Kenji,Sasabuchi, Yoshimasa,Yamamoto, Minoru,Ban, Masakazu,Okamoto, Kazuyoshi,Inoue, Kenji,Inaba, Takaaki,Takeno, Yuriko,Tsuboi, Takashi,Tonouchi, Asaka,Aono, Hiroyuki
supporting information; experimental part, p. 1232 - 1235 (2011/04/16)
Optimization of compounds 5 and 6 led to the discovery of VEGF inhibitor 10g which reduced CYP inhibition. It was highly active in vitro (VEGF induced HUVEC proliferation assay) and showed efficacies in three disease models in vivo (cancer, RA, and AMD).