257886-01-4 Usage
Chemical Properties
White to off-white crystals
Biochem/physiol Actions
Nα-Fmoc-O-trityl-D-homoserine is an N-terminal blocked O-tritylated derivative of homoserine.
Check Digit Verification of cas no
The CAS Registry Mumber 257886-01-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,5,7,8,8 and 6 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 257886-01:
(8*2)+(7*5)+(6*7)+(5*8)+(4*8)+(3*6)+(2*0)+(1*1)=184
184 % 10 = 4
So 257886-01-4 is a valid CAS Registry Number.
InChI:InChI=1/C38H33NO5/c40-36(41)35(39-37(42)43-26-34-32-22-12-10-20-30(32)31-21-11-13-23-33(31)34)24-25-44-38(27-14-4-1-5-15-27,28-16-6-2-7-17-28)29-18-8-3-9-19-29/h1-23,34-35H,24-26H2,(H,39,42)(H,40,41)/t35-/m1/s1
257886-01-4Relevant articles and documents
Application of the Trt and Fmoc Groups for the Protection of Polyfunctional α-Amino Acids
Barlos, Kleomenis,Mamos, Petros,Papaioannou, Dionysios,Patrianakou, Stella,Sanida, Chariklia,Schaefer, Wolfram
, p. 1025 - 1030 (2007/10/02)
Simple methods for the preparation of ditrityl amino acids 3 and their application for the synthesis of the peptides 9-27 are described.Selective detritylation of 3 and of the synthesized ditrityl peptides is achieved with 1percent trifluoroacetic acid in dichloromethane.The resulting Nα-detritylated amino acids 5 were converted into the corresponding fluorenylmethoxycarbonyl amino acids 6 under Schotten-Baumann conditions using fluorenylmethyl chloroformate.
