25791-28-0 Usage
Chemical class
Indole alkaloids
Natural occurrence
Found in a variety of plant species
Synthesized from
Natural product tryptanthrin
Biological activities
Anti-inflammatory, anti-cancer, and anti-microbial properties
Potential treatment for diseases
Rheumatoid arthritis and cancer
Inflammatory cytokine inhibition
Tryptanthrin has been shown to inhibit the production of inflammatory cytokines
Cancer cell growth suppression
Tryptanthrin has been shown to suppress the growth of cancer cells in experimental studies
Drug development potential
Tryptanthrin is a promising candidate for further drug development due to its various biological activities and potential therapeutic applications.
Check Digit Verification of cas no
The CAS Registry Mumber 25791-28-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,5,7,9 and 1 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 25791-28:
(7*2)+(6*5)+(5*7)+(4*9)+(3*1)+(2*2)+(1*8)=130
130 % 10 = 0
So 25791-28-0 is a valid CAS Registry Number.
25791-28-0Relevant academic research and scientific papers
Synthesis of 1-substituted 3-pyridinylmethylidenylindolin-2-ones and 1-substituted 3-quinolinylmethylidenylindolin-2-ones as the enhancers of ATRA-induced differentiation in HL-60 cells
Hung, Chi-Ying,Hsu, Mei-Hua,Huang, Li-Jiau,Hwang, Chrong-Shiong,Lee, On,Wu, Chen-Yi,Chen, Chih-Hung,Kuo, Sheng-Chu
, p. 4222 - 4232 (2008/12/20)
As part of our continuing search for potential differentiation agents, 1-benzyl-3-(4-pyridinylmethylidenyl)indolin-2-one (14) was selected as lead compound, and its new pyridinyl and quinolinyl analogs were synthesized and evaluated for differentiation-in
