257929-71-8

Upstream product

• 591-50-4 iodobenzene 
• 130225-27-3 (S_S)-ferrocenyl p-tolylsulfoxide 
• 358721-79-6 (S,R(p))-1-iodo-[(4-methylphenyl)sulfinyl]-ferrocene 
• 98-80-6 phenylboronic acid 

Downstream Products

• 803687-24-3 (S)-2-phenyl-1-(diphenylphosphanyl)ferrocene 

Relevant academic research and scientific papers

Use of Planar Chiral Ferrocenylphosphine-Gold(I) Complexes in the Asymmetric Cycloisomerization of 3-Hydroxylated 1,5-Enynes

Chiral monodentate phosphines based on ortho-disubstituted ferrocene units have been prepared and used for the synthesis of gold(I) complexes. These complexes are highly active catalysts for the cycloisomerization of 3-hydroxy-1,5-enynes into bicyclo[3.1.0]hexanones. Their high catalytic activity is ascribed to their structural analogy to the biaryl-based Buchwald phosphines. This paper discloses the first enantioselective variant of these reactions based on gold catalysis (ee's up to 80 %).

Asymmetric Synthesis and Chiroptical Properties of Enantiopure Helical Ferrocenes

An enantiopure helical ferrocene (Rp)-5 with five ortho-condensed aromatic rings was synthesized using a PtCl2-catalyzed cycloisomerization of planar-chiral 2-ethynyl-1-(4-phenanthrenyl)ferrocene (Rp)-6f, prepared in 3 steps from known enantiopure sulfinyl ferrocenyl boronic acid (SS,Sp)-7, as the source of planar chirality. This pentacyclic helical ferrocene showed a very high optical rotation value and strong circular dichroism (CD) signals.

Mercuration of ferrocenyl-p-tolyl sulfoxide and its conversion to 1,2-disubstituted ferrocenes

1-(p-Tolylsulfinyl)-2-(chloromercurio)ferrocene (2) was prepared by direct mercuration of ferrocenylsulfoxide (1). This reaction can be performed at room temperature in open air. Cross-coupling reactions of compound 2 and aryl halides especially aryl iodi

Mild access to planar-chiral: Ortho -condensed aromatic ferrocenes via gold(i)-catalyzed cycloisomerization of ortho -alkynylaryl ferrocenes

An efficient approach to (Rp) planar-chiral tri- and tetracyclic ortho-condensed aromatic ferrocenes was developed through the enantioselective cationic Au(i)-catalyzed cycloisomerization, in the presence of bidentate phosphine ligand (R)-DTBM-Segphos, from readily available ortho-alkynylaryl ferrocenes under very mild conditions (11 examples, up to 92% yield and 93% ee).

FERROCENYL PHOSPHITE LIGANDS FOR ASYMMETRIC CATALYSIS AND A METHOD FOR THEIR PRODUCTION

The present invention relates to novel ferrocene compounds, their synthesis and their use as catalysts. The compounds of the invention are useful additives in transition metal-promoted transformations of organic molecules such as hydrogenations, additions

Synthesis and first application of a new family of monophosphine ferrocene ligands (MOPF)

A new family of monophosphine ferrocene ligands (MOPF) has been synthesised in two steps from an optically pure ferrocenyl sulfoxide and the first preliminary studies employing these ligands in asymmetric hydrosilylation of styrene are presented.