258-16-2Relevant academic research and scientific papers
Synthesis of new benzo-substituted macrocyclic ligands containing quinoxaline subunits
Elwahy, Ahmed H. M.
, p. 897 - 907 (2007/10/03)
The macrocyclic Schiff bases 20-25 were prepared by cyclocondensation of the bis aldehydes 12-15 with the appropriate diaminoalkanes 17-19. Reduction of the latter with NaBH4 afforded the corresponding azacrown ethers 27-30. Heating of the aldehydes 12-16 in refluxing acetic acid afforded the corresponding 2,3-bis(benzofuranyl)quinoxalines 33-37. Nucleophilic reaction of the bis phenols 45-48, 54, 56, 57 with the appropriate dihalo compounds 1, 38 afforded the corresponding macrocyclic diamides 49-52 and 1,ω- bis[quinoxalino(2,3-b)benzoxazepino-13-on-yl]alkanes 60, 61, respectively. (C) 2000 Elsevier Science Ltd.
SYNTHESIS, STRUCTURE, AND CHEMICAL PROPERTIES OF SOME N-(3-CHLORO-2-QUINOXALYL)ARYLSULFONAMIDES
Litvinenko, S. V.,Savich, V. I.,Bobrovnik, L. D.
, p. 340 - 344 (2007/10/02)
We have developed a method for synthesis of N-(3-chloro-2-quinoxalyl)sulfonamides by reaction of 2,3-dichloroquinoxaline with substituted arylsulfonamides.Based on the IR spectra, we have established that in the solid state, the synthesized compounds exis
A Convenient and Single-Step Synthesis of Substituted 12H-Quinoxalino-benzothiazines and -benzoxazines
Agarwal, Nand L.,Sharma, Ashwani K.,Jamwal, Rajendra S.,Atal, Chand K.,Torres, Tomas
, p. 921 - 926 (2007/10/02)
Cyclocondensation of 2,3-dichloroquinoxaline (4) and the 2-aminothiophenols 1a-h or their zinc mercaptides 3a-h in the presence of alkaline dimethylformamide or in acidic medium afforded the corresponding 12H-quinoxalinobenzothiazines 7a-h in excellent yields.Similarly, the reaction of 4 with substituted 2-aminophenols 2 in the presence of base using dimethylformamide as solvent gave the 12H-quinoxalinobenzoxazines 7i-k.Acetyl derivatives of 7a-k were prepared.
