25810-58-6 Usage
Uses
Used in Pharmaceutical Research and Development:
(D,L)-2-(1-benzoylaminoethyl)benzimidazole is used as a chemical compound in pharmaceutical research and development for its potential biological activities. Its unique structure allows for exploration in various therapeutic areas, including cancer treatment, antimicrobial, and antiparasitic drug development.
Used in Cancer Treatment:
In the field of oncology, (D,L)-2-(1-benzoylaminoethyl)benzimidazole is used as a potential therapeutic agent for cancer treatment. Its specific interactions with cellular targets and biological pathways make it a candidate for further investigation into its efficacy and safety in combating various types of cancer.
Used in Antimicrobial Agents:
(D,L)-2-(1-benzoylaminoethyl)benzimidazole is utilized as a component in the development of antimicrobial agents. Its properties may contribute to the creation of new drugs that can effectively combat bacterial, fungal, and other microbial infections.
Used in Antiparasitic Drugs:
This benzimidazole derivative is also used as a key component in the development of antiparasitic drugs. Its potential to target and disrupt parasitic organisms makes it a valuable asset in the ongoing fight against parasitic diseases.
Used in Medicinal Chemistry:
(D,L)-2-(1-benzoylaminoethyl)benzimidazole serves as a valuable tool in medicinal chemistry, where it can be further investigated and developed for its potential applications in various therapeutic areas. Its unique structure and properties make it an attractive candidate for the design and synthesis of novel drugs with improved efficacy and safety profiles.
Check Digit Verification of cas no
The CAS Registry Mumber 25810-58-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,5,8,1 and 0 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 25810-58:
(7*2)+(6*5)+(5*8)+(4*1)+(3*0)+(2*5)+(1*8)=106
106 % 10 = 6
So 25810-58-6 is a valid CAS Registry Number.
25810-58-6Relevant academic research and scientific papers
Reaction of o-Phenylenediamine with 2-Oxazolin-5-ones
Tikdari, Ahmad M.,Mukerjee, Arya K.
, p. 73 - 74 (2007/10/02)
The reaction of o-phenylenediamine (2) with 2-oxazolin-5-ones (1a-c) gives benzimidazoles (4a-c) in the presence of gl. acetic acid.The intermediates 3a,b can be isolated only under neutral conditions. 4-(o-Aminoanilinomethylene)-2-phenyl-2-oxazolin-5-one (5) is formed, on heating 1d with 2, which is resistant to ring expansion.
Studies on Potential Antibacterial and Chelating Agents: Part I - Synthesis, Physicochemical Properties and Antibacterial Screening of Some Benzimidazoles
Nandi, M. M.,Ray, Ruma
, p. 222 - 224 (2007/10/02)
Six properly substituted benzimidazoles (I-VI) suitable for chelation have been synthesised from benzoylamino acids by condensation with o-phenylenediamine following Phillips and fusion methods.Dissociation constants of the benzoyl derivatives of glycine, (dl)-α-alanine, β-alanine, L-(-)-aspartic acid, L-(+)-glutamic acid and the six protonated benzamidobenzimidazoles (I-VI) in water-dioxane (1:1) at constant ionic strength (μ=0.5) at 20 deg C +/- 0.1 deg C have been determined by potentiometric titration.Structures of I-VI have been established on the basis of their elemental analysis, synthetic route, IR and PMR spectra and pK* values.Some of the compounds show significant antibacterial activity against gram + ve organisms only whereas corresponding sulphonamidobenzimidazoles are active against the gram - ve organism E. coli.
