258265-79-1Relevant academic research and scientific papers
Synthesis of ACE tricyclic systems of daphnicyclidin A and dehy-droxymacropodumine A
Wang, Qi,Zhang, Chao,Yang, Jun
, p. 1906 - 1910 (2020)
The synthesis of the ACE tricyclic system of daphnicyclidin A and dehydroxymacropodumine A are developed. The key reactions include an efficient aldol reaction to introduce chiral fragment 33 for further construction of piperidine ring B and seven-membered ring C, a nucleophilic addition of lithium pentene to aldehyde for installation of ring E, and a photocatalytic decarboxylation conjugate addition to construct ring C.
An approach to an asymmetric synthesis of stemofoline
Thomas, Eric J.,Vickers, Clare F.
experimental part, p. 970 - 979 (2009/09/30)
A stereoselective Mannich reaction between an (S)-tert-butylsulfinimine and methyl (S)-4-benzyloxy-3-methylbutanoate followed by treatment with acid and N-protection was used to prepare methyl (2R,3S)-2-[(S)-2-benzyloxy-1-methylethyl]-3-tert-butoxycarbony
