258273-50-6

Basic information

• Product Name: Methyl 6-methyl-2-(4-methylphenyl)imidazo[1,2-a]pyridine-3-acetate
• Synonyms: 6-methyl-2-(4-methylphenyl)imidazo[1,2-a]-pyridine-3-acetate,methyl ester;METHYL 6-METHYL-2-(4-METHYLPHENYL)IMIDAZO[1,2-A]PYRIDINE-3-ACETATE;6-Methyl-2-(4-methylphenyl)imidazo[1,2-a]pyridine-3-acetic acid methyl ester;6-Methyl-2-(4-methylphenyl)imidazo[1,2-A]-pyridine-3-acetate methyl este;methyl 2-(6-methyl-2-(p-tolyl)imidazo[1,2-a]pyridin-3-yl)acetate
• CAS NO: 258273-50-6
• Molecular Formula: C₁₈H₁₈N₂O₂
• Molecular Weight: 294.35
• Mol File: 258273-50-6.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• Density: 1.161 g/cm³
• Refractive Index: 1.599
• Storage Temp.: 2-8°C
• PKA: 6.48±0.50(Predicted)
• CAS DataBase Reference: Methyl 6-methyl-2-(4-methylphenyl)imidazo[1,2-a]pyridine-3-acetate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 6-methyl-2-(4-methylphenyl)imidazo[1,2-a]pyridine-3-acetate(258273-50-6)
• EPA Substance Registry System: Methyl 6-methyl-2-(4-methylphenyl)imidazo[1,2-a]pyridine-3-acetate(258273-50-6)

Safety Data

• Hazardous Substances Data: 258273-50-6(Hazardous Substances Data)

Usage

General Description

Methyl 6-methyl-2-(4-methylphenyl)imidazo[1,2-a]pyridine-3-acetate is a chemical compound with a complicated molecular structure. It is a derivative of imidazo[1,2-a]pyridine and contains a methyl group and a 4-methylphenyl group. Methyl 6-methyl-2-(4-methylphenyl)imidazo[1,2-a]pyridine-3-acetate is often used in organic synthesis and medicinal chemistry as a starting material for the preparation of various pharmaceuticals and bioactive compounds. Its specific properties and potential applications in various fields are subject to ongoing research and development.

InChI:InChI=1/C18H18N2O2/c1-12-4-7-14(8-5-12)18-15(10-17(21)22-3)20-11-13(2)6-9-16(20)19-18/h4-9,11H,10H2,1-3H3

Upstream product

• 695-34-1 2-Amino-4-methylpyridine 
• 88965-00-8 6-methyl-2-(4-methyl-phenyl)-imidazo[1,2-a]pyridine 
• 6832-16-2 methyl diazoacetate 
• 1603-41-4 (5-methyl-pyridin-2-yl)amine 
• 5720-05-8 4-methylphenylboronic acid 
• 78861-19-5 Methyl 3-bromo-4-keto-4-(4'-methylphenyl)butanoate 
• 67-56-1 methanol 
• 189005-44-5 6-methyl-2-(4-methylphenyl)-imidazo<1,2-a>pyridine-3-acetic acid 

Downstream Products

• 943430-36-2 (6-Methyl-2-p-tolyl-imidazo[1,2-a]pyridin-3-yl)-acetic acid hydrazide 
• 82626-48-0 N,N,6-trimethyl-2-(4-methylphenyl)imidazo[1,2-a]pyridine-3-acetamide 

Relevant articles and documents

Preparation method of zolpidem

The invention belongs to the field of pharmacy, and relates to a method for preparing zolpidem. The preparation method comprises the following steps: taking maleic anhydride and 2-amino-4-methylpyridine as raw materials, and carrying out a series of react

Practical and scalable preparation of Minodronic acid and Zolpidem from 2-chloroimidazole[1,2-a]pyridines

Practical and scalable procedures for Minodronic acid and Zolpidem are developed with short reaction sequences from 2-aminopyridines and maleic anhydride, respectively. The new procedures avoid column chromatography for the purification in all synthetic steps. Key aspects of this development involve reductive hydrodechlorination and Suzuki coupling reaction of 2-chloroimidazole[1,2-a]pyridines, and their application towards synthesis of the two drugs is also addressed.

PROCESS FOR THE PREPARATION OF 6-METHYL-2-(4-METHYL-PHENYL)-IMIDAZO 1,2-A]PYRIDINE-3-(N,N-DIMETHYL-ACETAMIDE) AND INTERMEDIATES

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