258356-19-3

Basic information

• Product Name: 3-(4-methyl-benzyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidine-7-thiol
• Synonyms: 3-(4-methyl-benzyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidine-7-thiol
• CAS NO: 258356-19-3
• Molecular Weight: 257.319
• Mol File: 258356-19-3.mol

Chemical Properties

• CAS DataBase Reference: 3-(4-methyl-benzyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidine-7-thiol(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-methyl-benzyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidine-7-thiol(258356-19-3)
• EPA Substance Registry System: 3-(4-methyl-benzyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidine-7-thiol(258356-19-3)

Safety Data

• Hazardous Substances Data: 258356-19-3(Hazardous Substances Data)

Upstream product

• 99613-60-2 1-(4-methylbenzyl)-4-carboxamido-5-amino-1H-1,2,3-triazole 
• 258356-16-0 3-(4-methyl-benzyl)-3,6-dihydro-[1,2,3]triazolo[4,5-d]pyrimidin-7-one 
• 17271-89-5 4-methylphenylmethylazide 
• 258356-17-1 7-chloro-3-(4-methyl-benzyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidine 

Downstream Products

• 258356-24-0 [3-(4-methyl-benzyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl]-hydrazine 
• 258356-21-7 3-(4-methyl-benzyl)-7-methylsulfanyl-3H-[1,2,3]triazolo[4,5-d]pyrimidine 

Relevant articles and documents

1,2,3-Triazolo[4,5-e]-1,2,4-triazolo[3,4-c]pyrimidines

Some new 1,2,3-triazolo[4,5-e]-1,2,4-triazolo[3,4-c]pyrimidines were prepared starting from the corresponding 1,2,3-triazolo[4,5-d]pyrimidines via the formation of the 1,2,4-triazole ring. Thus suitable hydrazino derivatives 6 were condensed with triethyl orthoformate, triethyl orthoacetate and triethyl orthobenzoate to give the expected tricyclic derivatives 7, 8 and 9. Intramolecular cyclization of the ethoxycarbonylhydrazino derivatives 10 gave the tricyclic compounds 11 bearing an hydroxyl group in the 3 position. The v-triazolo-s-triazolopyrimidine derivatives were tested towards the A1 and A(2A) adenosine receptors in binding assays, but they did not show any receptor affinity.