258501-34-7

Basic information

• Product Name: 5'-O-(tert-butyldiphenylsilyl)-2'-O-[2-[[N-methyl-N-(2-phthalimidoethyl)amino]oxy]ethyl]-5-methyluridine
• Synonyms: 5'-O-(tert-butyldiphenylsilyl)-2'-O-[2-[[N-methyl-N-(2-phthalimidoethyl)amino]oxy]ethyl]-5-methyluridine
• CAS NO: 258501-34-7
• Molecular Weight: 742.901
• Mol File: 258501-34-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5'-O-(tert-butyldiphenylsilyl)-2'-O-[2-[[N-methyl-N-(2-phthalimidoethyl)amino]oxy]ethyl]-5-methyluridine(CAS DataBase Reference)
• NIST Chemistry Reference: 5'-O-(tert-butyldiphenylsilyl)-2'-O-[2-[[N-methyl-N-(2-phthalimidoethyl)amino]oxy]ethyl]-5-methyluridine(258501-34-7)
• EPA Substance Registry System: 5'-O-(tert-butyldiphenylsilyl)-2'-O-[2-[[N-methyl-N-(2-phthalimidoethyl)amino]oxy]ethyl]-5-methyluridine(258501-34-7)

Safety Data

• Hazardous Substances Data: 258501-34-7(Hazardous Substances Data)

Upstream product

• 2913-97-5 N-phthalimidyl-2-aminoacetaldehyde 
• 258501-33-6 1-{5-(tert-butyl-diphenyl-silanyloxymethyl)-4-hydroxy-3-[2-(N-methyl-aminooxy)-ethoxy]-tetrahydro-furan-2-yl}-5-methyl-1H-pyrimidine-2,4-dione 
• 212061-25-1 5'-O-(tert-butyldiphenylsilyl)-2'-O-[2-[(2,3-dihydro-1,3-dioxo-1H-isoindol-2-yl)oxy]ethyl]-5-methyluridine 
• 212061-26-2 2'-O-[(2-formadoxyiminooxy)ethyl]-5'-O-tert-butyldiphenylsilyl-5-methyluridine 

Downstream Products

• 258501-36-9 5'-O-(4,4'-dimethoxytrityl)-2'-O-[2-[[N-methyl-N-(2-phthalimidoethyl)amino]oxy]ethyl]-5-methyluridine 

Relevant articles and documents

Synthesis of 2′-O-[2-[(N,N-dialkylamino)oxy]ethyl]-modified oligonucleotides: Hybridization affinity, resistance to nuclease, and protein binding characteristics

Synthesis of a series of 2′ -O-[2-[(N,N-dialkylamino)oxy]ethyl]-modified 5-methyluridine nucleoside phosphoramidites and solid supports are described. Using these monomers, modified oligonucleotides containing phosphodiester linkages were synthesized in h