258508-85-9Relevant academic research and scientific papers
HETEROCYCLIC COMPOUND
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Paragraph 0311, (2020/06/23)
Provided is a heterocyclic compound that can have an antagonistic action on an NMDA receptor containing the NR2B subunit, and is expected to be useful as a prophylactic or therapeutic agent for major depression, bipolar disorder, migraine, pain, periphera
OXADIAZOLE DERIVATIVES AND PHARMACEUTICAL USES THEREOF
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Paragraph 0232, (2017/02/02)
PROBLEM TO BE SOLVED: To provide therapeutic or preventive agents for various diseases or symptoms associated with a serotonin 4 receptor (particularly, neuropsychiatric diseases such as Alzheimer-type dementia). SOLUTION: The present invention provides a compound represented by formula (1) or a pharmaceutically acceptable salt thereof. In the formula (1), Het represents formula (Het-1) or the like, A represents formula (A-1) or the like, B represents (B-1) or the like, R1A represents a hydrogen atom, an alkyl group or the like, R2A, R5, R6 and R7 represent a hydrogen atom, a halogen atom, an alkyl group or the like, R8 and R9 represent a hydrogen atom, an alkyl group or the like, and l represents an integer of 0-4. SELECTED DRAWING: None COPYRIGHT: (C)2016,JPOandINPIT
Conformationally semi-constrained quinoxaline 2,3-diones as neuroprotective agents
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Example 1, (2008/06/13)
Described are neuroprotective agents of Formula I wherein R is an amino acid or nitrogen heterocyclic ring which is saturated or unsaturated of from 5 to 8 members which may have additional oxygen or sulfur atoms therein. The other provisions or substitue
Synthesis of novel quinoxaline-5-carboxylic acid derivatives
Kornberg, Brian E.,Nikam, Sham S.,Rafferty, Michael F.
, p. 1271 - 1277 (2007/10/03)
This paper describes the synthesis of several new 2,3-dimethoxy-6- methyl-7-nitro-quinoxaline-5-carboxylic acid derivatives (13a-m) via a multistep synthetic route from 5-methyl-1H-benzo[d][1,3]oxazine-2,4-dione (1).
