25854-80-2Relevant academic research and scientific papers
Rh- and Cu-Cocatalyzed Aerobic Oxidative Approach to Quinazolines via [4 + 2] C-H Annulation with Alkyl Azides
Wang, Xiaoyang,Jiao, Ning
, p. 2150 - 2153 (2016)
A novel and efficient rhodium- and copper-co-catalyzed C-H bond activation and annulation for the construction of bioactively important quinazolines has been developed. This [4 + 2] annulation strategy utilizing alkyl azides as the carbon-heteroatom synthons shows high efficiency in the synthesis of six-membered benzoheterocycles containing two heteroatoms. This aerobic oxidative protocol provides a useful application of simple alkyl azides in N-heterocycle synthesis with N2 and H2O as byproducts.
RhIII/CuII-cocatalyzed synthesis of 1H-indazoles through C-H amidation and N-N bond formation
Yu, Da-Gang,Suri, Mamta,Glorius, Frank
, p. 8802 - 8805 (2013/07/25)
Substituted 1H-indazoles can be formed from readily available arylimidates and organo azides by RhIII-catalyzed C-H activation/C-N bond formation and Cu-catalyzed N-N bond formation. For the first time the N-H-imidates are demonstrated to be go
