2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-(3-bromo-2-methoxypropyl)-5-phenylis a pyrimidine derivative with a bromo-methoxypropyl and phenyl substituent. It is a highly specific and potent inhibitor of the endothelial-enriched cadherin VE-cadherin. 2,4,6(1H,3H,5H)-Pyrimidinetrione,
5-(3-bromo-2-methoxypropyl)-5-phenylhas shown potential in inhibiting endothelial cell alignment and barrier formation and has been studied for its potential applications in anti-angiogenic therapy. Additionally, research has indicated that it may also have potential in the treatment of certain types of cancer and inflammatory diseases. Further studies are ongoing to explore its therapeutic potential and mechanism of action.
5-(3-bromo-2-methoxypropyl)-5-phenylhas shown potential in inhibiting endothelial cell alignment and barrier formation and has been studied for its potential applications in anti-angiogenic therapy. Additionally, research has indicated that it may also have potential in the treatment of certain types of cancer and inflammatory diseases. Further studies are ongoing to explore its therapeutic potential and mechanism of action.
25860-24-6
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Basic information
- Product Name: 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-(3-bromo-2-methoxypropyl)-5-phenyl-
- Synonyms:
- CAS NO:25860-24-6
- Molecular Formula: C14H15BrN2O4
- Molecular Weight: 355.188
- EINECS: N/A
- Product Categories: N/A
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: N/A
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-(3-bromo-2-methoxypropyl)-5-phenyl-(CAS DataBase Reference)
- NIST Chemistry Reference: 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-(3-bromo-2-methoxypropyl)-5-phenyl-(25860-24-6)
- EPA Substance Registry System: 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-(3-bromo-2-methoxypropyl)-5-phenyl-(25860-24-6)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 25860-24-6(Hazardous Substances Data)
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25860-24-6 Usage
Uses
Used in Anti-angiogenic Therapy:2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-(3-bromo-2-methoxypropyl)-5-phenylis used as an inhibitor of VE-cadherin for its potential applications in anti-angiogenic therapy. It has shown potential in inhibiting endothelial cell alignment and barrier formation, which can help prevent the formation of new blood vessels in tumors and other abnormal tissues.
Used in Cancer Treatment:
2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-(3-bromo-2-methoxypropyl)-5-phenylis used as a potential treatment for certain types of cancer. Its ability to inhibit VE-cadherin and endothelial cell alignment may help in preventing tumor growth and progression by disrupting the formation of new blood vessels that supply nutrients to the tumor.
Used in Inflammatory Disease Treatment:
2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-(3-bromo-2-methoxypropyl)-5-phenylis used as a potential treatment for certain types of inflammatory diseases. Its ability to inhibit VE-cadherin and endothelial cell alignment may help in reducing inflammation by preventing the formation of new blood vessels that contribute to the inflammatory response.
Note: The specific application industries for 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-(3-bromo-2-methoxypropyl)-5-phenyl- are not provided in the materials. However, based on its potential uses, it can be inferred that it may be used in the pharmaceutical and biotechnology industries for the development of new therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 25860-24-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,5,8,6 and 0 respectively; the second part has 2 digits, 2 and 4 respectively.Calculate Digit Verification of CAS Registry Number 25860-24:
(7*2)+(6*5)+(5*8)+(4*6)+(3*0)+(2*2)+(1*4)=116
116 % 10 = 6
So 25860-24-6 is a valid CAS Registry Number.
25860-24-6Upstream product
25860-24-6Downstream Products
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2,4,6(1H,3H,5H)-Pyrimidinetrione,
5-(3-bromo-2-methoxypropyl)-5-phenyl-
