258849-18-2Relevant academic research and scientific papers
Total syntheses of all four stereoisomers of piscidic acid via catalytic asymmetric dihydroxylation of (Z)- and (E)-trisubstituted olefins
Toshima, Hiroaki,Saito, Masatoshi,Yoshihara, Teruhiko
, p. 1934 - 1941 (2007/10/03)
All four stereoisomers of (2S, 3R)-(+)-piscidic acid were synthesized with high optical purity via Sharpless catalytic asymmetric dihydroxylation of (Z)- and (E)-trisubstituted olefins in 6 steps from (4-hydroxyphenyl)pyruvic acid. The Wittig reaction of
