258871-60-2 Usage
Uses
Used in Pharmaceutical Industry:
(-)-PF1163B is used as a potential treatment for obesity and metabolic disorders due to its ability to target the NPY Y2 receptor, which is involved in the regulation of feeding behavior and energy homeostasis.
Used in Psychiatric Disorder Treatment:
(-)-PF1163B is used as a potential candidate for the treatment of psychiatric disorders, such as anxiety and depression, due to its anxiolytic and antidepressant effects.
Used in Research and Development:
(-)-PF1163B is used as a valuable tool for further research into the NPY system and potential therapeutic applications, given its favorable pharmacokinetic properties and selectivity for the NPY Y2 receptor.
Check Digit Verification of cas no
The CAS Registry Mumber 258871-60-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,5,8,8,7 and 1 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 258871-60:
(8*2)+(7*5)+(6*8)+(5*8)+(4*7)+(3*1)+(2*6)+(1*0)=182
182 % 10 = 2
So 258871-60-2 is a valid CAS Registry Number.
258871-60-2Relevant academic research and scientific papers
Total Synthesis of PF1163B
Sengupta, Aakash,Hosokawa, Seijiro
supporting information, p. 709 - 712 (2019/03/26)
A total synthesis of PF1163B has been achieved. The vinylogous Mukaiyama aldol reaction of ketene silyl N, O -acetal 6 (ent - 6) mediated by excess TiCl 4 proceeded with saturated aldehydes to give adduct 10 in moderate yield with moderate ster
