626242-99-7

Basic information

• Product Name: 3-[4-(2-benzyloxy-ethoxy)-phenyl]-2-(tert-butoxycarbonyl-methyl-amino)-propionic acid methyl ester
• Synonyms: 3-[4-(2-benzyloxy-ethoxy)-phenyl]-2-(tert-butoxycarbonyl-methyl-amino)-propionic acid methyl ester
• CAS NO: 626242-99-7
• Molecular Weight: 443.54
• Mol File: 626242-99-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3-[4-(2-benzyloxy-ethoxy)-phenyl]-2-(tert-butoxycarbonyl-methyl-amino)-propionic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-[4-(2-benzyloxy-ethoxy)-phenyl]-2-(tert-butoxycarbonyl-methyl-amino)-propionic acid methyl ester(626242-99-7)
• EPA Substance Registry System: 3-[4-(2-benzyloxy-ethoxy)-phenyl]-2-(tert-butoxycarbonyl-methyl-amino)-propionic acid methyl ester(626242-99-7)

Safety Data

• Hazardous Substances Data: 626242-99-7(Hazardous Substances Data)

Upstream product

• 1462-37-9 bromoethyl-2-benzyl ether 
• 147363-23-3 methyl (2S)-2-{[(tert-butoxy)carbonyl]amino}-3-[4-(prop-2-en-1-yloxy)phenyl]-propanoate 
• 1388220-73-2 (S)-methyl 2-[tert-butoxycarbonyl(methyl)amino]-3-[4-(2-hydroxyethoxy)phenyl]propanoate 
• 100-39-0 benzyl bromide 
• 4326-36-7 (S)-N-(tert-butoxycarbonyl)tyrosine methyl ester 
• 626242-98-6 methyl 3-(4-(2-(benzyloxy)ethoxy)phenyl)-2-(tert-butoxycarbonylamino)propanoate 
• 74-88-4 methyl iodide 

Downstream Products

• 1388220-68-5 (S)-[(3R,5S)-5-(benzyloxy)oct-1-en-3-yl] 3-[4-(2-(benzyloxy)ethoxy)phenyl]-2-[(R)-N,6-dimethyloct-7-enamido]propanoate 
• 1388220-73-2 (S)-methyl 2-[tert-butoxycarbonyl(methyl)amino]-3-[4-(2-hydroxyethoxy)phenyl]propanoate 
• 258871-60-2 (-)-PF₁₁₆₃B 

Relevant articles and documents

Total Synthesis and Conformational Analysis of the Antifungal Agent (-)-PF1163B

(Equation presented) (-)-PF1163B, a new macrocyclic antifungal antibiotic isolated from Streptomyces sp., has been prepared in eight steps from (S)-citronellene. The key step is a ring-closing metathesis reaction of an ester and amide derivative obtained from a substituted N-methyl-L-tyrosine.

Total synthesis of the antifungal antibiotic PF1163A

The total synthesis of a novel antifungal antibiotic PF1163A is reported utilising Keck asymmetric allylation, Sharpless kinetic resolution, regioselective epoxide-ring opening, esterification and ring-closing metathesis as the key reactions.