2591-11-9

Basic information

• Product Name: 2-(Ethylsulfonyl)benzothiazole
• Synonyms: 2-(Ethylsulfonyl)benzothiazole
• CAS NO: 2591-11-9
• Molecular Formula: C₉H₉NO₂S₂
• Molecular Weight: 227.3
• Mol File: 2591-11-9.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 377°C at 760 mmHg
• Flash Point: 181.8°C
• Appearance: /
• Density: 1.381g/cm³
• Vapor Pressure: 1.51E-05mmHg at 25°C
• Refractive Index: 1.627
• CAS DataBase Reference: 2-(Ethylsulfonyl)benzothiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(Ethylsulfonyl)benzothiazole(2591-11-9)
• EPA Substance Registry System: 2-(Ethylsulfonyl)benzothiazole(2591-11-9)

Safety Data

• Hazardous Substances Data: 2591-11-9(Hazardous Substances Data)

Usage

Common uses

Intermediate in the synthesis of pharmaceuticals and agrochemicals
Potential as an antifungal agent
Studied for antimicrobial and anti-inflammatory properties
Used in the production of rubber and rubber additives

Physical properties

Stable, colorless to light yellow liquid at room temperature, soluble in various organic solvents

Value

Diverse range of applications and potential biological activities make it a valuable chemical in various industries.

InChI:InChI=1/C9H9NO2S2/c1-2-14(11,12)9-10-7-5-3-4-6-8(7)13-9/h3-6H,2H2,1H3

Upstream product

• 2591-09-5 2-vinylsulfonylbenzo[d][1,3]thiazole 
• 1271300-36-7 2-(tricosanylsulfonyl)benzo[d]thiazole 
• 75-08-1 ethanethiol 
• 74-96-4 ethyl bromide 
• 149-30-4 2-Mercaptobenzothiazole 
• 615-20-3 2-chlorobenzo[d][1,3]thiazole 
• 20035-08-9 sodium ethanesulfinate 
• 60372-29-4 2-(2-chloroethylsulfenyl)benzo[d][1,3]thiazole 
• 2602-78-0 2-(2-chloro-ethanesulfonyl)-benzothiazole 
• 2757-92-8 2-(ethylthio)benzothiazole 

Downstream Products

• 1450821-37-0 (9aS,E)-8-ethylidene-3-methoxy-1-phenyl-7,8,9,9a-tetrahydro-1H-2-oxa-6a,10adiazabenzo[cd]cyclopenta[g]azulene-6,10-dione 
• 594-43-4 ethyl methyl sulfone 
• 6379-72-2 1,2-dimethoxy-4-(E)-propenylbenzene 
• 4180-23-8 E-1-(4'-methoxyphenyl)prop-1-ene 

Relevant articles and documents

Synthesis of enol ethers from lactones using modified Julia olefination reagents: application to the preparation of tri- and tetrasubstituted exoglycals

A new route to substituted exoglycals from the corresponding lactones is described. The enol ethers synthesis via a modified Julia olefination of sugar-derived lactones is extended to substituted benzothiazolyl sulfones to furnish tri- and tetrasubstitute

Tunable Heteroaromatic Sulfones Enhance in-Cell Cysteine Profiling

Heteroaromatic sulfones react with cysteine via nucleophilic aromatic substitution, providing a mechanistically selective and irreversible scaffold for cysteine conjugation. Here we evaluate a library of heteroaromatic sulfides with different oxidation st

1,3,5-SUBSTITUTED PHENYL DERIVATIVE COMPOUNDS USEFUL AS BETA-SECRETASE INHIBITORS FOR THE TREATMENT OF ALZHEIMER'S DISEASE

The present invention is directed to 1,3,5-phenyl substituted derivative compounds which are inhibitors of the beta-secretase enzyme and that are useful in the treatment of diseases in which the beta-secretase enzyme is involved, such as Alzheimer's disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the treatment of such diseases in which the beta-secretase enzyme is involved.