2591-09-5Relevant academic research and scientific papers
Radical Mediated Diastereoselective Synthesis of Benzothiazole Sulfonyl Ethyl C-Glycosides
Krishna, Palakodety Radha,Lavanya,Jyothi,Sharma
, p. 423 - 431 (2003)
Diastereoselective synthesis of a variety of benzothiazole sulfonyl ethyl C-glycosides has been developed by a radical mediated approach on the reaction of glycosyl bromides and benzothiazolyl vinyl sulfone in the presence of n-Bu3SnH and AIBN
Diastereoselective Monofluorocyclopropanation Using Fluoromethylsulfonium Salts
Melngaile, Renate,Sperga, Arturs,Baldridge, Kim K.,Veliks, Janis
, p. 7174 - 7178 (2019/09/12)
Diarylfluoromethylsulfonium salts, alternatives to freons or advanced fluorinated building blocks, are bench stable and easy-to-use sources of direct fluoromethylene (:CHF) transfer to alkenes. These salts enabled development of a trans-selective monofluorinated Johnson-Corey-Chaykovsky reaction with vinyl sulfones or vinyl sulfonamides to access synthetically challenging monofluorocyclopropane scaffolds. The described method offers rapid access to monofluorinated cyclopropane building blocks with further functionalization opportunities to deliver more complex synthetic targets diastereoselectively.
Catalytic asymmetric formal: γ -allylation of deconjugated butenolides
Simlandy, Amit K.,Mukherjee, Santanu
supporting information, p. 5659 - 5664 (2016/07/06)
A formal γ-allylation of deconjugated butenolides is reported based on a two-step sequence consisting of a catalytic diastereo- and enantioselective vinylogous nucleophilic addition to vinyl sulfones and Julia-Kocienski olefination. This highly modular approach delivers densely functionalized butenolides containing a quaternary stereogenic centre in excellent yield with high enantioselectivity.
