25910-57-0

Usage

Uses

Used in Textile Industry:
4-[(4-nitrophenyl)azo]benzene-1,3-diamine is used as a dye for nylon fibers, providing a vibrant red color to the fibers. It is chosen for its ability to produce a consistent and long-lasting color, as well as its compatibility with the nylon material.
The dye also meets certain industry standards for performance, including:
1. Ironing Fastness: The dye maintains its color and does not fade or change when exposed to heat during the ironing process. It has a rating of 4-5 on the ISO scale.
2. Light Fastness: The dye is resistant to fading when exposed to sunlight, ensuring that the color remains vibrant and consistent over time. It has a rating of 4 on the ISO scale.
3. Perspiration Fastness: The dye does not fade or change color when exposed to sweat, making it suitable for use in clothing that will be worn during physical activity. It has a rating of 4-5 on the ISO scale.
4. Washing Fastness: The dye maintains its color and does not fade or change when washed, ensuring that the dyed nylon fibers remain vibrant and consistent even after multiple washes. It has a rating of 5 on the ISO scale.
5. Fading and Staining: The dye has a low tendency to fade or cause staining on other fabrics, making it a reliable choice for use in the textile industry. It has ratings of 4 and 5 on the ISO scale for fading and staining, respectively.

Preparation

4-Nitrobenzenamine diazo, And Benzene-1,3-diamine coupling..

Standard( polyacrylonitrile fiber )

Ironing Fastness

Fading

Stain

ISO

4-5

InChI:InChI=1/C12H11N5O2/c13-8-1-6-12(11(14)7-8)16-15-9-2-4-10(5-3-9)17(18)19/h1-7H,13-14H2/b16-15+

Upstream product

• 108-45-2 m-phenylenediamine 
• 100-01-6 4-nitro-aniline 
• 14368-49-1 p-nitrobenzenediazonium 
• 541-69-5 m-phenylenediamine dihydrochloride 

Downstream Products

• 40655-13-8 5-amino-2-(4'-nitrophenyl)benzotriazole 

Relevant academic research and scientific papers

TRPswitch - A Step-Function Chemo-optogenetic Ligand for the Vertebrate TRPA1 Channel

Chemo-optogenetics has produced powerful tools for optical control of cell activity, but current tools suffer from a variety of limitations including low unitary conductance, the need to modify the target channel, or the inability to control both on and off switching. Using a zebrafish behavior-based screening strategy, we discovered "TRPswitch", a photoswitchable nonelectrophilic ligand scaffold for the transient receptor potential ankyrin 1 (TRPA1) channel. TRPA1 exhibits high unitary channel conductance, making it an ideal target for chemo-optogenetic tool development. Key molecular determinants for the activity of TRPswitch were elucidated and allowed for replacement of the TRPswitch azobenzene with a next-generation azoheteroarene. The TRPswitch compounds enable reversible, repeatable, and nearly quantitative light-induced activation and deactivation of the vertebrate TRPA1 channel with violet and green light, respectively. The utility of TRPswitch compounds was demonstrated in larval zebrafish hearts exogenously expressing zebrafish Trpa1b, where the heartbeat could be controlled using TRPswitch and light. Therefore, TRPA1/TRPswitch represents a novel step-function chemo-optogenetic system with a unique combination of high conductance, high efficiency, activity against an unmodified vertebrate channel, and capacity for bidirectional optical switching. This chemo-optogenetic system will be particularly applicable in systems where a large depolarization current is needed or sustained channel activation is desirable.

"TRPSWITCH" ? A STEP FUNCTION CHEMO-OPTOGENETIC LIGAND

Described herein are photoswitchable compounds that can activate TRPA1 channels in neuronal and non-neuronal cells. The TRPswitch molecules allow for optical control of both the activation and deactivation of TRPA1 channels. Such compounds can be used as research tools or therapeutics.

APPLICATION OF FLUORESCENT TRIAZOLES TO ANALYTICAL CHEMISTRY. III. FLUORESCENCE CHARACTERISTICS OF 2-PHENYLBENZOTRIAZOLYL-5-AMINE DERIVATIVES AS FLUORESCENT PROBES

2-Phenylbenzotriazole derivatives with a COCH3 or NH2 group on the 2-phenyl ring were synthesized and found to be applicable as fluorescent hydrophobic probes.The fluorescence intensities of these compounds, which were intense in non-polar solvents, were dramatically quenched in polar solvents.In particular, 2-(4-acetylphenyl)-2H-benzotriazolyl-5-amine (7) showed a much higher ratio of the fluorescence intensity in the organic solvent to that in water (Fo/Fw) than 8-anilino-1-naphthalenesulfonate (ANS): The Fo/Fw values of 7 were 470 for dioxane and 440 for acetone, while those of ANS were 100 for dioxane and 90 for acetone.We modified compound 7 to obtain water-soluble probes for use in drug-protein binding studies and examined the interaction of these probes with human serum albumin (HSA).All the compounds, which were practically non-fluorescent in the buffer solution, bound to HSA and fluoresced.Keywords: 2-phenylbenzotriazolyl-5-amine; fluorescence characteristies; solvent effect; fluorescent probe; protein binding