259137-83-2

Usage

Uses

Used in Pharmaceutical Synthesis:
(2-Trifluoromethoxy-phenyl)-carbamic acid ethyl ester serves as an intermediate in the synthesis of pharmaceuticals, contributing to the development of new therapeutic agents. Its unique properties make it a valuable component in medicinal chemistry for creating compounds with specific biological activities.
Used in Agrochemical Production:
(2-Trifluoromethoxy-phenyl)-carbamic acid ethyl ester is also utilized as an intermediate in the production of agrochemicals, where it aids in the synthesis of various organic compounds intended for agricultural applications, such as pesticides and herbicides.
Used in Organic Compound Synthesis:
(2-Trifluoromethoxy-phenyl)-carbamic acid ethyl ester is a potential precursor for the synthesis of a range of organic compounds, highlighting its versatility and importance in organic chemistry for creating diverse chemical entities with potential applications across different industries.

Upstream product

• 1535-75-7 2-trifluoromethoxy aniline 
• 541-41-3 chloroformic acid ethyl ester 

Downstream Products

• 1313040-15-1 [4-(5-aminomethyl-2-fluorophenyl)-piperidin-1-yl]-[1-(2-methoxy-ethyl)-7-trifluoromethoxy-1H-indol-3-yl]methanone hydrochloride 
• 1313040-16-2 [4-(5-aminomethyl-2-fluoro-phenyl)-piperidin-1-yl]-[1-(2-methoxyethyl)-7-trifluoromethoxy-1H-indol-3-yl]-methanone 
• 1313041-44-9 2,2,2-trifluoro-N-(4-fluoro-3-{1-[1-(2-methoxyethyl)-7-trifluoromethoxy-1 H-indole-3-carbonyl]-piperidin-4-yl}benzyl)acetamide 
• 1313040-47-9 2-(4-aminomethyl-2-{1-[1-(2-methoxy-ethyl)-7-trifluoromethoxy-1H-indole-3-carbonyl]-piperidin-4-yl}-phenoxy)-acetamide hydrochloride 
• 1313042-50-0 (4-carbamoylmethoxy-3-{1-[1-(2-methoxy-ethyl)-7-trifluoromethoxy-1H-indole-3-carbonyl]-piperidin-4-yl}-benzyl)-carbamic acid tert-butyl ester 
• 1313040-46-8 2-(4-aminomethyl-2-{1-[1-(2-methoxy-ethyl)-7-methyl-1H-indole-3-carbonyl]-piperidin-4-yl}-phenoxy)-acetamide hydrochloride 
• 1313042-46-4 (4-carbamoylmethoxy-3-{1-[1-(2-methoxy-ethyl)-7-methyl-1H-indole-3-carbonyl]-piperidin-4-yl}-benzyl)-carbamic acid tert-butyl ester 
• 1313040-44-6 2-(4-aminomethyl-2-{1-[1-(2-methoxy-ethyl)-7-trifluoromethoxy-1H-indole-3-carbonyl]-piperidin-4-yl}-phenoxy)-N,N-dimethyl-acetamide hydrochloride 
• 1313042-42-0 (4-dimethylcarbamoylmethoxy-3-{1-[1-(2-methoxy-ethyl )-7-trifluoromethoxy-1H-indole-3-carbonyl]-piperidin-4-yl}-benzyl)-carbamic acid tert-butyl ester 
• 1313040-43-5 2-(4-aminomethyl-2-{1-[1-(2-methoxy-ethyl)-7-trifluoromethoxy-1H-indole-3-carbonyl]-piperidin-4-yl}-phenoxy)-N-methyl-acetamide hydrochloride 
• 1313042-41-9 (3-{1-[1-(2-methoxy-ethyl)-7-trifluoromethoxy-1H-indole-3-carbonyl]-piperidin-4-yl}-4-methylcarbamoylmethoxy-benzyl)-carbamic acid tert-butyl ester 
• 1313042-40-8 (4-(tert-butoxycarbonylamino-methyl)-2-{1-[1-(2-methoxy-ethyl)-7-trifluoromethoxy-1H-indole-3-carbonyl]-piperidin-4-yl}-phenoxy)-acetic acid 
• 1313040-40-2 2-(4-aminomethyl-2-{1-[1-(2-methoxy-ethyl)-7-methyl-1H-indole-3-carbonyl]-piperidin-4-yl}-phenoxy)-N,N-dimethyl-acetamide hydrochloride 
• 1313042-35-1 (4-dimethylcarbamoylmethoxy-3-{1-[1-(2-methoxy-ethyl)-7-methyl-1H-indole-3-carbonyl]-piperidin-4-yl}-benzyl)-carbamic acid tert-butyl ester 

Relevant academic research and scientific papers

INDOLYL-PIPERIDINYL BENZYLAMINES AS BETA-TRYPTASE INHIBITORS

The present invention discloses and claims a series of substituted indolyl-piperidinyl benzylamines of formula (I), wherein R1, R2 and R3 are as described herein. More specifically, the compounds of this invention are inhibitors of β-tryptase and are, therefore, useful as pharmaceutical agents. Additionally, this invention also discloses methods of preparation of substituted indolyl-piperidinyl benzylamines. In one of the embodiments, there is provided the compounds of formula (I) wherein R3 is (II).

SPIROPIPERIDINE BENZYLAMINES AS BETA-TRYPTASE INHIBITORS

The present invention discloses and claims a series of substituted spiropiperidine benzylamines of formula (I) wherein R is as described herein. More specifically, the compounds of this invention are inhibitors of β-tryptase and are, therefore, useful as

Piperazine derivatives

Piperazine derivatives, as well as pharmaceutically acceptable salts, solvates and esters thereof, can be used in the form of pharmaceutical preparations for the treatment or prevention of disorders of the central nervous system, damage to the central ner

Anti-obesity 1,2,3,4,10,10-a-hexahydropy razino [1,2-a] indoles

The present invention is directed to 1,2,3,4,10,10a,-hexahydropyrazino[1,2-a] indole derivatives as well as pharmaceutically acceptable salts, solvates and esters thereof, wherein R1 to R8 have the significance given in claim 1 be used in the form of pharmaceutical preparations for the treatment or prevention of disorders of the central nervous system, damage to the central nervous system, cardiovascular disorders, gastrointestinal disorders, diabetes insipidus, obesity and sleep apnea.