25917-55-9

Basic information

• Product Name: 4-cyano-N-phenylbutanamide
• Synonyms: 4-cyano-N-phenylbutanamide
• CAS NO: 25917-55-9
• Molecular Weight: 188.229
• Mol File: 25917-55-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 4-cyano-N-phenylbutanamide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-cyano-N-phenylbutanamide(25917-55-9)
• EPA Substance Registry System: 4-cyano-N-phenylbutanamide(25917-55-9)

Safety Data

• Hazardous Substances Data: 25917-55-9(Hazardous Substances Data)

Upstream product

• 186581-53-3 diazomethane 
• 16051-87-9 3-cyanopropanoic acid 
• 62-53-3 aniline 
• 201230-82-2 carbon monoxide 
• 109-75-1 but-3-enenitrile 
• 55679-48-6 N-phenylnonanamide 
• 98-95-3 nitrobenzene 
• 103-71-9 phenyl isocyanate 
• 39201-33-7 4-cyanobutyric acid 

Downstream Products

• 54959-85-2 5-(4-chlorophenyl)-5-oxopentanenitrile 

Relevant articles and documents

A Novel Ketonitrile Synthesis by Palladium-Catalyzed Carbonylative Coupling Reactions of Amides with Arylboronic Acids

A novel, efficient, and simple procedure to synthesize diverse ketonitriles by palladium-catalyzed Suzuki coupling of amides through N–C cleavage has been developed. This procedure features mild conditions, a broad substrate scope, and easily prepared substrates, providing a simple and efficient access to a variety of ketonitriles.

Selective palladium-catalyzed aminocarbonylation of olefins with aromatic amines and nitroarenes

Various olefins can be smoothly transformed in the presence of a Pd-based catalyst system and (hetero)aromatic amines or nitroarenes to synthetically interesting amides in good yields and often with high regioselectivity (see scheme). Combining this atom-efficient procedure with established functionalizations of the resulting products allows the efficient preparation of quinolines. Copyright