55679-48-6

Upstream product

• 112-05-0 nonanoic acid 
• 62-53-3 aniline 
• 7661-07-6 3-bromo-N-phenylpropanamide 
• 21437-78-5 3-iodo-propionic acid anilide 
• 629-27-6 1-Iodooctane 
• 201230-82-2 carbon monoxide 
• 98-95-3 nitrobenzene 
• 111-66-0 oct-1-ene 
• 592-99-4 4-octene 
• 111-67-1 2-octene 
• 153035-33-7 (E)-2-Trimethylsilanyl-penta-2,4-dienoic acid phenylamide 
• 198978-35-7 2-Oxo-decanenitrile 
• 103-71-9 phenyl isocyanate 
• 17049-49-9 octylmagnesium bromide 

Downstream Products

• 25917-55-9 4-cyano-N-phenylbutanamide 
• 91-73-6 N,N-dibenzylaniline 
• 758640-21-0 N-Benzylaniline 
• 4096-21-3 N-phenylpyrrolidine 
• 3526-43-0 N-(4-methoxybenzyl)aniline 
• 3007-72-5 N-(n-nonyl)aniline 
• 27522-47-0 Dinonyl-phenyl-amine 
• 62-53-3 aniline 
• 7465-88-5 4-methoxy-N-phenylbenzamide 
• 6833-18-7 4-methyl-N-phenylbenzamide 
• 143-08-8 nonyl alcohol 

Relevant academic research and scientific papers

Synergistic Copper-Catalyzed Reductive Aminocarbonylation of Alkyl Iodides with Nitroarenes

We have developed a Cu-catalyzed reductive aminocarbonylation of alkyl iodides using nitroarenes as the nitrogen source. The reaction proceeds with a single copper catalyst playing dual roles of synergistically mediating both carbonylation of alkyl iodide

Organic ligand-free carbonylation reactions with unsupported bulk Pd as catalyst

Herein, surprising results for bulk Pd-catalyzed carbonylation reactions are presented. Three types of carbonylation reactions can be realized efficiently under organic ligand-free conditions, namely, hydroaminocarbonylation of olefins, aminocarbonylation of aryl iodides and oxidative carbonylation of amines, which almost cover all the known mechanisms in carbonylation reactions. Notably, the bulk Pd catalyst system exhibited better catalytic activity than the classical homogeneous PdCl2/(2-OMePh)3P catalyst system. This study will create a momentous and new field of green carbonylation reactions.

Selective Palladium-Catalyzed Aminocarbonylation of Olefins to Branched Amides

A general and efficient protocol for iso-selective aminocarbonylation of olefins with aliphatic amines has been developed for the first time. Key to the success for this process is the use of a specific 2-phosphino-substituted pyrrole ligand in the presence of PdX2(X=halide) as a pre-catalyst. Bulk industrial and functionalized olefins react with various aliphatic amines, including amino-acid derivatives, to give the corresponding branched amides generally in good yields (up to 99 %) and regioselectivities (b/l up to 99:1).

Selective formation of α,ω-ester amides from the aminocarbonylation of castor oil derived methyl 10-undecenoate and other unsaturated substrates

The reaction of long chain alkenes with CO and aniline in the presence of palladium complexes of 1,2-bis-(ditertbutylphosphinomethyl)benzene produces amides with high linear selectivity, with much higher rates and catalyst stability when 2-naphthol and sodium or potassium iodide are added. Unsaturated esters including methyl 10-undecenoate from castor oil give α,ω- ester amides, whilst reactions in THF give N-phenylpyrrolidine.

Selective palladium-catalyzed aminocarbonylation of olefins with aromatic amines and nitroarenes

Various olefins can be smoothly transformed in the presence of a Pd-based catalyst system and (hetero)aromatic amines or nitroarenes to synthetically interesting amides in good yields and often with high regioselectivity (see scheme). Combining this atom-efficient procedure with established functionalizations of the resulting products allows the efficient preparation of quinolines. Copyright

Non-Lactone Carbocyclic and Heterocyclic Antagonists and Agonists of Bacterial Quorum Sensing

Compounds which modulate quorum sensing in quorum sensing bacteria. Compounds of the invention inhibit quorum sensing and/or activate quorum sensing in various bacteria. Compounds that inhibit quorum sensing are particularly useful for inhibition of detri

A novel approach for the direct conversion of alkylsulfonyl derivatives into alkylcarbonyl derivatives via tin-free radical carbonylation

A novel radical approach for the direct conversion of RSO2X into RCOX in a single step is devised; the present approach is very simple, highly efficient, and minimizes formation of by-product. The Royal Society of Chemistry.

Catalytic one-pot synthesis of N-phenyl alkyl amides from alkene and aniline in the presence of cobalt on charcoal under carbon monoxide

N-Phenyl alkyl amides were synthesized by the cobalt on charcoal-catalyzed one-pot reaction of alkene and aniline under carbon monoxide; this is the first heterogeneous catalytic formation of N-phenyl alkyl amides.

A Convenient Synthesis of Amides with 2-Halo-2,3-dihydro-1,3,4,2-oxadiazaphospholes as a New Condensing Agents

Various amides, including some with bulky substituents, are prepared in good yields from free carboxylic acids and amines under mild conditions by a one-step method using new condensing agents 2-halo-2,3-dihydro-1,3,4,2-oxadiazaphospholes, especially 5-methyl-2-chloro-3-phenyl-2,3-dihydro-1,3,4,2-oxadiazaphosphole.