259226-86-3Relevant academic research and scientific papers
Oligomers of gadolinium chelates, their applicationascontrast products in magnetic resonance imaging and their synthesis intermediates
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Page/Page column 35, (2010/11/26)
The invention relates to high-relaxivity macrocyclic gadolinium chelate oligomers of formula [in-line-formulae]W-(A)m[/in-line-formulae] in which W, A and m are as defined in claim 1, and their use as a blood pool contrast product for magnetic resonance imaging.
Monodisperse perfluoro-polyethoxylated amphiphilic compounds with two-chain polar head - Preparation and properties
Selve,Ravey,Stebe,El Moudjahid,Moumni,Delpuech
, p. 411 - 428 (2007/10/02)
Monodisperse new surfactant molecules with a two-chain polyoxyethylene (EO) hydrophilic head and a perfluoroalkyl hydrophobic moiety linked together through an amide bond are synthesized by methods allowing large-scale production. Surface tension measurements (γ ~ 20 mN·m-1) show slow organization of the surfactant film at the water/air interface for longer fluorocarbon tail. Values of critical micellar concentrations and comparisons with monosubstituted amide surfactants are consistent with a high hydrophilicity of the amide function, a small influence of branching over hydrophilicity, and a hydrophobicity of each CF2 unit equivalent to 1.7 methylenes (in the analogous hydrogenated surfactants).
