41121-04-4

Usage

Uses

Used in Pharmaceutical Synthesis:
Bis[2-[2-(2-methoxyethoxy)ethoxy]ethyl]amine serves as a crucial building block in the creation of various pharmaceuticals. Its unique structure allows it to be incorporated into the molecular design of drugs, potentially enhancing their efficacy and selectivity.
Used in Agrochemical Production:
In the agrochemical industry, bis[2-[2-(2-methoxyethoxy)ethoxy]ethyl]amine is utilized in the synthesis of pesticides and other crop protection agents. Its ability to form stable derivatives makes it valuable in developing products that are both effective and environmentally friendly.
Used as a Solubilizer in Industrial Processes:
Bis[2-[2-(2-methoxyethoxy)ethoxy]ethyl]amine is employed as a solubilizer in various industrial applications. Its capacity to dissolve a wide range of substances makes it an indispensable component in the formulation of products such as detergents, emulsifiers, and other specialty chemicals.
Used as a Dispersing Agent in Formulations:
bis[2-[2-(2-methoxyethoxy)ethoxy]ethyl]amine also functions as a dispersing agent, helping to evenly distribute ingredients within a formulation. This is particularly important in industries where homogeneity of the final product is critical for performance and quality.

InChI:InChI=1/C14H31NO6/c1-16-7-9-20-13-11-18-5-3-15-4-6-19-12-14-21-10-8-17-2/h15H,3-14H2,1-2H3

Upstream product

• 111-77-3 2-(2-methoxyethoxy)ethyl alcohol 
• 62921-74-8 2-(2-(2-methoxyethoxy)ethoxy)ethyl p-toluenesulfonate 
• 112-35-6 triethylene glucol monomethyl ether 
• 50586-80-6 toluene-4-sulfonic acid 2-(2-methoxyethoxy)ethyl ester 
• 123852-07-3 N,N bis(triethyleneglycol-monomethylether)tritylamine 
• 259226-86-3 N,N bis(triethyleneglycol-monomethylether)benzylamine 

Relevant academic research and scientific papers

Push-pull pyropheophorbides for nonlinear optical imaging

Pyropheophorbide-a methyl ester (PPa-OMe) has been modified by attaching electron-donor and -acceptor groups to alter its linear and nonlinear optical properties. Regioselective bromination of the terminal vinyl position and Suzuki coupling were used to attach a 4-(N,N-diethylaminophenyl) electron-donor group. The electron-acceptor dicyanomethylene was attached at the cyclic ketone position through a Knoevenagel condensation. Four different derivatives of PPa-OMe, containing either electron-donor or electron-acceptor groups, or both, were converted to hydrophilic bis-TEG amides to generate a series of amphiphilic dyes. The absorption and emission properties of all the dyes were compared to a previously reported push-pull type porphyrin-based dye and a commercial push-pull styryl dye, FM4-64. Electrochemical measurements reveal that the electron donor group causes a greater decrease in HOMO-LUMO gap than the electron-acceptor. TD-DFT calculations on optimized geometries (DFT) of all four dyes show that the HOMO is mostly localized on the donor, 4-(N,N-diethylaminophenyl), while the LUMO is distributed around the chlorin ring and the electron-acceptor. Hyper-Rayleigh scattering experiments show that the first-order hyperpolarizabilities of the dyes increase on attaching either electron-donor or -acceptor groups, having the highest value when both the donor and acceptor groups are attached. Two-photon excited fluorescence (TPEF) and second harmonic generation (SHG) images of the bis-TEG amide attached dyes in lipid monolayer-coated droplets of water-in-oil reveal that the TPEF and SHG involve transition dipole moments in different orientations.

Strong two-photon absorption enhancement in a unique bis-porphyrin bearing a diketopyrrolopyrrole unit

A π-extended bis-porphyrin bridged via a diketopyrrolopyrrole unit was prepared in 5 steps. This fully conjugated π-system displays strongly distorted linear absorption, while its two-photon absorption cross-section reaches 2500-3000 GM at 940 nm. LC-like behaviour, easy orientation and low viscosity are, according to XRD, POM and DSC measurements, due to formation of plastic rather than a liquid crystal.

Oligomers of gadolinium chelates, their applicationascontrast products in magnetic resonance imaging and their synthesis intermediates

The invention relates to high-relaxivity macrocyclic gadolinium chelate oligomers of formula [in-line-formulae]W-(A)m[/in-line-formulae] in which W, A and m are as defined in claim 1, and their use as a blood pool contrast product for magnetic resonance imaging.

PEPTIDE DERIVATIVES

The invention concerns pharmaceutically useful peptide derivatives of the formula (I), P-AA I -AA 2 -AA 3 -AA 4 -AA 5 -AA 6 -AA 7 -AA 8 -Q, in which P, AA 1, AA 2, AA 3 , AA 4, AA 5, AA 6, AA 7, AA 8, and Q have the various meanings defined herein and their pharmaceutically accentable salts, and pharmaceutical compositions containing them. The novel peptide derivatives are of value in treating MHC class II dependent T-cell mediated autoimmune or inflammatory diseases, such as rheumatoid arthritis. The invention further concerns processes for the manufacture of the novel peptide derivatives and the use of the compounds in medical treatment.

Monodisperse perfluoro-polyethoxylated amphiphilic compounds with two-chain polar head - Preparation and properties

Monodisperse new surfactant molecules with a two-chain polyoxyethylene (EO) hydrophilic head and a perfluoroalkyl hydrophobic moiety linked together through an amide bond are synthesized by methods allowing large-scale production. Surface tension measurements (γ ~ 20 mN·m-1) show slow organization of the surfactant film at the water/air interface for longer fluorocarbon tail. Values of critical micellar concentrations and comparisons with monosubstituted amide surfactants are consistent with a high hydrophilicity of the amide function, a small influence of branching over hydrophilicity, and a hydrophobicity of each CF2 unit equivalent to 1.7 methylenes (in the analogous hydrogenated surfactants).

Synthesis of Novel Perfluoroalkyl Nonionic Surfactants with a Bipodal Hydrophilic Moiety

Monodisperse perfluoroalkyl N,N'-polyethoxylated amides, synthesized as dimethyl ether derivatives, CnF(2n+1)CH2C(O)N(mMe)2 are efficient bipodal nonionic fluorinated surfactants.