259227-22-0Relevant academic research and scientific papers
Synthesis and biological evaluation of 3,4-diaryloxazolones: A new class of orally active cyclooxygenase-2 inhibitors
Puig, Carles,Miralpeix, Montserrat,Puig, Jaume,Beleta, Jordi,Huerta, Josep M.,López, Manel,Segarra, Victor,Ryder, Hamish,Palacios, José M.,Crespo, María I.,Godessart, Núria,Feixas, Joan,Ibarzo, Javier,Jiménez, Juan-Miguel,Soca, Lídia,Cardelús, Ignasi,Heredia, Ascensión
, p. 214 - 223 (2007/10/03)
A series of 3,4-diaryloxazolones were prepared and evaluated for their ability to inhibit cyclooxygenase-2 (COX-2). Extensive structure-activity relationship work was carried out within this series, and a number of potent and selective COX-2 inhibitors we
