259249-40-6

Basic information

• Product Name: (R)-2-((4S,5S)-4,5-Bis-hydroxymethyl-2-methyl-[1,3]dioxolan-2-yl)-1-(4-methoxy-phenyl)-2,3-dihydro-1H-pyridin-4-one
• Synonyms: (R)-2-((4S,5S)-4,5-Bis-hydroxymethyl-2-methyl-[1,3]dioxolan-2-yl)-1-(4-methoxy-phenyl)-2,3-dihydro-1H-pyridin-4-one
• CAS NO: 259249-40-6
• Molecular Weight: 349.384
• Mol File: 259249-40-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-2-((4S,5S)-4,5-Bis-hydroxymethyl-2-methyl-[1,3]dioxolan-2-yl)-1-(4-methoxy-phenyl)-2,3-dihydro-1H-pyridin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-2-((4S,5S)-4,5-Bis-hydroxymethyl-2-methyl-[1,3]dioxolan-2-yl)-1-(4-methoxy-phenyl)-2,3-dihydro-1H-pyridin-4-one(259249-40-6)
• EPA Substance Registry System: (R)-2-((4S,5S)-4,5-Bis-hydroxymethyl-2-methyl-[1,3]dioxolan-2-yl)-1-(4-methoxy-phenyl)-2,3-dihydro-1H-pyridin-4-one(259249-40-6)

Safety Data

• Hazardous Substances Data: 259249-40-6(Hazardous Substances Data)

Upstream product

• 139308-00-2 (4S,5S)-4,5-Dimethoxymethyl-2-(N-p-methoxyphenyl)iminomethyl-2-methyl-1,3-dioxolane 
• 259249-29-1 (R)-2-((4S,5S)-4,5-Bis-methoxymethyl-2-methyl-[1,3]dioxolan-2-yl)-1-(4-methoxy-phenyl)-2,3-dihydro-1H-pyridin-4-one 

Downstream Products

• 259249-30-4 2-[4,5-bis-(tert-butyl-diphenyl-silanyloxymethyl)-2-methyl-[1,3]dioxolan-2-yl]-1-(4-methoxy-phenyl)-2,3-dihydro-1H-pyridin-4-one 

Relevant articles and documents

Stereospecific synthesis of piperidine skeleton by [4+2] cycloaddition, leading to the synthesis of piperidines of biological interests

[4+2] Cycloaddition reaction between a chiral imine possessing an auxiliary derived from tartaric acid and Danishefsky diene was studied, and the reaction promoted by boron trifluoride etherate gave 2, 3- dehydropiperidin-4-one in a stereospecific manner. The adduct thus obtained was converted into (S)-coniine derivatives without loss of the stereochemical integrity.