259263-96-2

Basic information

• Product Name: Urea, N-[2-(4-hydroxyphenyl)ethyl]-N'-(4-nitrophenyl)-
• CAS NO: 259263-96-2
• Molecular Formula: C15H15N3O4
• Molecular Weight: 301.302
• Mol File: 259263-96-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Urea, N-[2-(4-hydroxyphenyl)ethyl]-N'-(4-nitrophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Urea, N-[2-(4-hydroxyphenyl)ethyl]-N'-(4-nitrophenyl)-(259263-96-2)
• EPA Substance Registry System: Urea, N-[2-(4-hydroxyphenyl)ethyl]-N'-(4-nitrophenyl)-(259263-96-2)

Safety Data

• Hazardous Substances Data: 259263-96-2(Hazardous Substances Data)

Upstream product

• 51-67-2 tyrosamine 
• 100-28-7 4-Nitrophenyl isocyanate 

Downstream Products

• 393511-90-5 1-{4-[bis-(2-hydroxy-ethyl)-amino]-phenyl}-3-[2-(4-hydroxy-phenyl)-ethyl]-urea 
• 393511-88-1 4-di(2-chloroethyl)aminoanilino-4-hydroxyphenethylaminomethanone 
• 393511-89-2 4-aminoanilino-4-hydroxyphenethylaminomethanone 

Relevant articles and documents

Synthesis and analysis of urea and carbamate prodrugs as candidates for melanocyte-directed enzyme prodrug therapy (MDEPT).

The suitability of 4-di(2-chloroethyl)aminoanilino-4-hydroxyphenethylaminomethanone 2 to act as a prodrug for melanocyte-directed enzyme prodrug therapy (MDEPT) is assessed. Thus its synthesis, ability to generate a cytotoxic agent upon exposure to tyrosinase, and stability within different sera are reported. A comparison is made to illustrate that the new urea prodrug 2 is a more suitable candidate for MDEPT than the corresponding carbamate prodrug 1.