259675-17-7

Upstream product

• 98-88-4 benzoyl chloride 
• 259675-16-6 [6α-2H]-5α-cholestane-3β,7α-diol 
• 259675-13-3 [6α-2H]-7α-bromo-5α-cholestane-3β,6β-diol 
• 259675-15-5 [6β-2H]-3β-acetoxy-6α,7α-epoxy-5α-cholestane 
• 259675-14-4 [6-2H]-3β-acetoxy-5α-cholest-6-ene 
• 39673-19-3 3β-acetoxy-7α-bromo-5α-cholestan-6-one 

Relevant academic research and scientific papers

Biosynthesis of 20-hydroxyecdysone in Ajuga hairy roots: Fate of 6α- and 6β-hydrogens of lathosterol

The fate of 6α- and 6β-hydrogens of lathosterol during the transformation into 20-hydroxyecdysone was chased by feeding [3α,6β-2H2]- and [3α,6α-2H2]-lathosterols to hairy roots of Ajuga reptans var. atropurpurea. The behavior of 6β-hydrogen, which mostly migrated to the C-5 position of 20-hydroxyecdysone, was in agreement with that of C-6 hydrogen of cholesterol. The results strongly supported the view that cholesterol and lathosterol are first metabolized into 7-dehydrocholesterol, which is then converted into 20-hydroxyecdysone via 7-dehydrocholesterol 5α,6α-epoxide in the hairy roots. Copyright (C) 1999 Elsevier Science Ltd.