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{5-[2-(6-bromo-2-naphthalen-2-yl-4-oxo-4H-quinazolin-3-yl)-acetylamino]-pentyl}-carbamic acid tert-butyl ester is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

259730-86-4

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259730-86-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 259730-86-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,5,9,7,3 and 0 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 259730-86:
(8*2)+(7*5)+(6*9)+(5*7)+(4*3)+(3*0)+(2*8)+(1*6)=174
174 % 10 = 4
So 259730-86-4 is a valid CAS Registry Number.

259730-86-4Relevant academic research and scientific papers

Modeling directed design and biological evaluation of quinazolinones as non-peptidic growth hormone secretagogues

Ye, Zhixiong,Gao, Yingduo,Bakshi, Raman K.,Chen, Meng-Hsin,Rohrer, Susan P.,Feighner, Scott D.,Pong, Sheng-Shung,Howard, Andrew D.,Blake, Allan,Birzin, Elizabeth T.,Locco, Louis,Parmar, Rupa M.,Chan, Wanda W.-S.,Schaeffer, James M.,Smith, Roy G.,Patchett, Arthur A.,Nargund, Ravi P.

, p. 5 - 8 (2000)

Quinazolinone derivatives were synthesized and evaluated as non-peptidic growth hormone secretagogues. Modeling guided design of quinazolinone compound 21 led to a potency enhancement of greater than 200-fold compared to human growth hormone secretagogue affinity of a screening lead 4.

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