25974-26-9

Usage

Uses

Used in Pharmaceutical Industry:
Pyridazine, 3,6-dichloro-, 2-oxide is used as an intermediate in the production of pharmaceuticals for its unique structural properties that can be further modified to create various drug molecules.
Used in Agrochemical Production:
Pyridazine, 3,6-dichloro-, 2-oxide is used as an intermediate in the synthesis of agrochemicals, contributing to the development of new pesticides and other agricultural chemicals.
Used in Specialty Chemicals Synthesis:
Pyridazine, 3,6-dichloro-, 2-oxide is used as a building block in the synthesis of specialty chemicals, leveraging its structural features to create compounds with specific properties for various applications.

InChI:InChI=1/C4H2Cl2N2O/c5-3-1-2-4(6)8(9)7-3/h1-2H

Upstream product

• 141-30-0 3,6-dichlorpyridazine 

Downstream Products

• 499234-73-0 3-chloro-6-(2-cyclopropylphenoxy)-pyridazine 1-oxide 
• 499234-72-9 6-chloro-3-(2-cyclopropylphenoxy)-pyridazine 1-oxide 
• 499234-89-8 6-Chloro-3-[2-(methylsulfanyl)phenoxy]pyridazine 1-oxide 
• 499235-47-1 6-Chloro-3-[2-(2,2-dichlorocyclopropyl)-6-methylphenoxy]pyridazine 1-oxide 
• 499235-88-0 3-chloro-6-(2-cyclopropyl-3,5,6-trimethylphenoxy)pyridazine 1-oxide 
• 499235-87-9 6-chloro-3-(2-cyclopropyl-3,5,6-trimethylphenoxy)pyridazine 1-oxide 
• 499235-96-0 3-chloro-6-(2-methoxy-3,5,6-trimethylphenoxy)pyridazine 1-oxide 
• 499235-95-9 6-chloro-3-(2-methoxy-3,5,6-trimethylphenoxy)pyridazine 1-oxide 
• 499236-38-3 4,6-Dichloro-3-[2,4-dibromo-5-(ethylsulfanyl)phenoxy]pyridazine 
• 499236-04-3 6-chloro-3-[2-(2-methyl-1-propenyl)phenoxy]pyridazine 1-oxide 
• 499236-05-4 3-chloro-6-[2-(2-methyl-1-propenyl)phenoxy]pyridazine 1-oxide 
• 499236-08-7 1-{3-[(6-chloro-2-oxide-3-pyridazinyl)oxy]phenyl}ethanone 
• 499236-07-6 1-{3-[(6-chloro-1-oxide-3-pyridazinyl)oxy]phenyl}ethanone 
• 499236-12-3 6-chloro-3-(2-iodo-3-methoxyphenoxy)pyridazine 1-oxide 

Relevant academic research and scientific papers

Synthesis of N,N-Dioxopyridazines

Despite many efforts, one of the smallest heterocycles containing two nitrogen atoms, pyridazine, could not be converted to its N,N-dioxide (see, however, Nakadate et al. Chem. Pharm. Bull. 1970, 18, 1211-1218). HOF·CH3CN, made easily from diluted fluorine, was able to accomplish this task in a fast reaction with good yields.

Synthesis of Nitrogen Heterocycles via Photochemical Ring Opening of Pyridazine N-Oxides

A photochemical method for the direct synthesis of 1H-pyrazoles from pyridazine N-oxides was developed. This chemistry features a regioselective approach to nonsymmetrically substituted pyridazine N-oxides. Herein, we highlight the first strategic use of photoinduced ring-opening reactions of 1,2-diazine N-oxides for the preparative synthesis of nitrogen heterocycles.

METHOD FOR PRODUCING 3,6-DICHLOROPYRIDAZINE-1-OXIDE

A process for preparing 3,6-dichloropyridazine-1-oxide which comprises reacting 3,6-dichloropyridazine with an acid anhydride and hydrogen peroxide of a concentration of 60% or less or a urea hydrogen peroxide addition compound.

MONOCYCLIC DIAZODIOXIDE BASED BCL-2 PROTEIN ANTAGONISTS

Compounds and compositions containing compounds given by the structural Formula 8, for tumor therapeutic applications are disclosed. A and B are each independently selected from C is selected from D is selected from -N-, -NO-, NR10, -/