259743-62-9

Upstream product

• 2876-08-6 1,2-dimethyl-1H-benzimidazole 
• 104-88-1 4-chlorobenzaldehyde 
• 74-88-4 methyl iodide 
• 615-15-6 2-Methyl-1H-benzimidazole 
• 1632-83-3 1-Methylbenzimidazole 
• 66482-29-9 1-[(E)-2-bromoethenyl]-4-chlorobenzene 
• 1615-02-7 3-(4-chlorophenyl)prop-2-enoic acid 
• 937026-55-6 C₁₅H₁₃ClN₂O 
• 77-78-1 dimethyl sulfate 
• 206982-69-6 (E)-2-(4-chlorostyryl)-1H-benzo[d]imidazole 
• 95-54-5 1,2-diamino-benzene 

Relevant academic research and scientific papers

Nano CuO-catalyzed C-H functionalization of 1,3-azoles with bromoarenes and bromoalkenes

Copper oxide catalyzed direct C-H arylation and alkenylation of aromatic heterocycles using aryl and alkenyl bromides have been developed and have been applied to the C-H functionalization of a variety of 1,3-azoles like benzoxazole, benzothiazole, 1-methylbenzimidazole, and 1-methylimidazole, with moderate to excellent yields. The best performance has been achieved in the presence of PPh3 when average size of CuO nanoparticles is 6.5 nm. This catalyst can be recovered and reused without significant decrease in its catalytic activity.

Inhibition of monoamine oxidase B by selected benzimidazole and caffeine analogues

We have recently reported that a series of (E)-8-styrylcaffeines and (E)-2-styrylbenzimidazoles are moderate to very potent competitive inhibitors of monoamine oxidase B (MAO-B). The most potent member of the series was found to be (E)-8-(3-chlorostyryl)c

Synthesis and spectral properties of a variety of 2-styrylbenzimidazoles

Studies on the synthesis of various 2-styrylbenzimidazoles 3, 7 and N-methylated 2-styrylbenzimidazoles 5, 9 from 2-methyl/ethyl benzimidazoles 2, 6 and 1,2-dimethyl/1-methyl-2-ethylbenzimidazoles 4, 8 respectively by condensation with different aromatic aldehydes are described. The spectral characteristics of 2-styrylbenzimidazoles and N-methylated-2-styrylbenzimidazoles are discussed. An efficient and convenient phase-transfer catalysed methylation procedure for the synthesis of N-methylated-2-styrylbenzimidazoles from 2-styrylbenzimidazoles is reported.