259793-88-9 Usage
Uses
6-Bromo-3-hydroxypyrazine-2-carboxamide is a building block related to Favipiravir(F103350). Favipiravir is used for the treatment of advanced Ebola virus infection in a small animal model. Favipiravir suppressed the replication of Zaire Ebola virus and prevented a lethal outcome in 100% of the animals. Based on the studies, Favipiravir can be a candidate for the treatment of Ebola hemorrhagic fever.
Check Digit Verification of cas no
The CAS Registry Mumber 259793-88-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,5,9,7,9 and 3 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 259793-88:
(8*2)+(7*5)+(6*9)+(5*7)+(4*9)+(3*3)+(2*8)+(1*8)=209
209 % 10 = 9
So 259793-88-9 is a valid CAS Registry Number.
259793-88-9Relevant articles and documents
Preparation method of favipiravir
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Paragraph 0031-0035, (2021/02/10)
The invention relates to the technical field of biological medicines, in particular to a preparation method of favipiravir, which comprises the following steps of: stirring 3-hydroxy pyrazine-2-formamide and a fluorinating reagent in a solvent, and carrying out one-step reaction to obtain favipiravir. The preparation method of favipiravir provided by the invention is short and novel in route, mildin reaction condition, economical and effective, higher in yield than the existing preparation method, and suitable for large-scale industrial production.