259794-06-4

Usage

Uses

Used in Flavor and Fragrance Industry:
METHYL 6-BROMO-3-METHOXYPYRAZINE-2-CARBOXYLATE is used as a flavoring agent and fragrance ingredient for its characteristic strong, earthy, and green aroma. It enhances the sensory experience of various food products and perfumes, contributing to their unique and appealing scents.
Used in Pharmaceutical Industry:
In the pharmaceutical sector, METHYL 6-BROMO-3-METHOXYPYRAZINE-2-CARBOXYLATE serves as a crucial intermediate in the synthesis of other organic compounds. Its role in the production process is vital for creating a range of pharmaceuticals that address various health needs.

Upstream product

• 67-56-1 methanol 
• 6966-01-4 methyl 3-amino-6-bromopyrazine-2-carboxylate 

Downstream Products

• 614730-10-8 methyl 3-methoxy-6-methylpyrazine-2-carboxylate 

Relevant academic research and scientific papers

MICROBIOCIDAL DERIVATIVES

Compounds of the formula (I) wherein the substituents are as defined in claim 1, useful as pesticides, and especially fungicides.

TRIAZOLONE COMPOUNDS AND USES THEREOF

The invention disclosed herein is directed to compounds of Formula (I) and pharmaceutically acceptable salts thereof, which are useful in the treatment of prostate, breast, colon, pancreatic, human chronic lymphocytic leukemia, melanoma and other cancers. The invention also comprises pharmaceutical compositions comprising a therapeutically effective amount of compound of Formula (I), or a pharmaceutically acceptable salt thereof. The invention disclosed herein is also directed to methods of treating prostate, breast, ovarian, liver, kidney, colon, pancreatic, human chronic lymphocytic leukemia, melanoma and other cancers. The invention disclosed herein is further directed to methods of treating prostate, breast, colon, pancreatic, chronic lymphocytic leukemia, melanoma and other cancers comprising administration of a of a therapeutically effective amount of a selective PPARα antagonist. The compounds and pharmaceutical compositions of the invention are also useful in the treatment of viral infections, such as HCV infections and HIV infections. The invention disclosed herein is also directed to a methods of preventing the onset of and/or recurrence of acute and chronic myeloid leukemia, as well as other cancers, comprising administration of a of a therapeutically effective amount of a selective PPARα antagonist.

Novel pyrazine derivatives or salts thereof, pharmaceutical composition containing the same, and production intermediates thereof

Pyrazine derivatives represented by general formula [1]: 1wherein the variables are as defined in the specification, or salts thereof have an excellent antiviral activity and are useful as a therapeutic agent for treating viral infections. Further, fluoropyrazine-carboxamide derivatives represented by general formula [2]: 2wherein the variables are as defined in the specification, or salts thereof are useful as an intermediate for production of the compounds of general formula [1], and as an intermediate for production of the fluoropyrazine-carboxamide derivatives of which one typical example is 6-fluoro-3-hyroxy-2-pyrazine-carboxamide having an antiviral activity.

Nitrogen-containing heterocyclic carboxamide derivatives or salts thereof and antiviral agents comprising the same

Nitrogen-containing heterocyclic carboxamide derivatives represented by the following general formula: 1wherein ring A is a substituted or unsubstituted pyrazine, pyrimidine, pyridazine or triazine ring; R1 is O or OH; R2 is a hydrogen atom, an acyl group or a substituted or unsubstituted carbamoylalkyl or carboxyalkyl group; and the broken line represents a single bond or a double bond; or salts thereof are useful for preventing and treating virus infections and especially influenza virus infections.